SCHEMBL317816

SCHEMBL317816

NC[C@H]1O[C@@H](n2ccc(N)nc2=O)CC1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.62
LMNA P02545 3/20 0.53
PDE3A Q14432 3/20 0.53
DNMT1 P26358 3/20 0.53
CACNA1F O60840 2/20 0.53
ALB P02768 2/20 0.53
MAPT P10636 2/20 0.53
CACNA1D Q01668 2/20 0.53
CACNA1S Q13698 2/20 0.53
CACNA1C Q13936 2/20 0.53
ADRB1 P08588 1/20 0.53
THRB P10828 1/20 0.52
MTOR P42345 1/20 0.52
MDM2 Q00987 1/20 0.52
NCOA1 Q15788 1/20 0.52
NCOA3 Q9Y6Q9 1/20 0.52
P2RY2 P41231 3/20 0.51
P2RY4 P51582 3/20 0.51
P2RY6 Q15077 2/20 0.51
PDE4D Q08499 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6914288 1.00 POLB (0.62) POLBLMNAPDE3ADNMT1CACNA1F
Phosphoric Acid SCHEMBL1970387 0.95 POLB (0.67) POLBLMNAPDE3ADNMT1CACNA1F
Doxecitine SCHEMBL193815 0.90 DNMT1 (0.66) POLBLMNAPDE3ADNMT1CACNA1F
Doxecitine SCHEMBL23178 0.90 DNMT1 (0.66) POLBLMNAPDE3ADNMT1CACNA1F
Doxecitine SCHEMBL15832461 0.90 DNMT1 (0.66) POLBLMNAPDE3ADNMT1CACNA1F
Doxecitine SCHEMBL23346798 0.90 DNMT1 (0.66) POLBLMNAPDE3ADNMT1CACNA1F
Doxecitine SCHEMBL13700553 0.90 DNMT1 (0.66) POLBLMNAPDE3ADNMT1CACNA1F
Doxecitine SCHEMBL10238960 0.90 DNMT1 (0.66) POLBLMNAPDE3ADNMT1CACNA1F
Doxecitine SCHEMBL887491 0.90 DNMT1 (0.66) POLBLMNAPDE3ADNMT1CACNA1F
SCHEMBL3693586 0.90 POLB (0.62) POLBLMNAPDE3ADNMT1CACNA1F

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025056970-A1 MAMMALIAN CELL CULTURE ADDITIVES VIROCELL BIOLOGICS LTD (GB) 2025-03-20 WO claimed
US-20200016182-A1 STAT5a AND ITS FUNCTIONAL TUMOR SUPPRESSOR ANALOGS FOR TREATMENT OF MALIGNANCIES EXPRESSING NPM/ALK AND OTHER ONCOGENIC KINASES NIH - DEITR 2020-01-16 US claimed
US-10166251-B2 STAT5a and its functional tumor suppressor analogs for treatment of malignancies expressing NPM/ALK and other oncogenic kinases THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2019-01-01 US claimed
US-20170106008-A1 STAT5a AND ITS FUNCTIONAL TUMOR SUPPRESSOR ANALOGS FOR TREATMENT OF MALIGNANCIES EXPRESSING NPM/ALK AND OTHER ONCOGENIC KINASES THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2017-04-20 US claimed
US-9486469-B2 STAT5a and its functional tumor suppressor analogs for treatment of malignancies expressing NPM/ALK and other oncogenic kinases THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2016-11-08 US claimed
US-20130165502-A1 Diagnostic, Prognostic and Therapeutic Uses of miRs in Adaptive Pathways and Disease Pathways THE OHIO STATE UNIVERSITY (US) 2013-06-27 US claimed
US-20110086043-A1 STAT5a AND ITS FUNCTIONAL TUMOR SUPPRESSOR ANALOGS FOR TREATMENT OF MALIGNANCIES EXPRESSING NPM/ALK AND OTHER ONCOGENIC KINASES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2011-04-14 US claimed
US-20110077215-A1 DNA Methylation As A Target For Diagnosis And Treatment Of Chronic Lymphocytic Leukema (CLL) THE UNIVERSITY OF UTAH RESEARCH FOUNDATION 2011-03-31 US claimed
US-20100278937-A1 COMPOSITIONS AND METHODS TO PREVENT AND/OR TREAT CANCER WITH PA-CARD THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2010-11-04 US claimed
WO-2010096754-A1 COMPOSITIONS AND METHODS TO PREVENT AND/OR TREAT CANCER WITH PA -CARD CDG THEREAPEUTICS, INC. (US) 2010-08-26 WO claimed
WO-2009045965-A2 STAT5A AND ITS FUNCTIONAL TUMOR SUPPRESSOR ANALOGS FOR TREATMENT OF MALIGNANCIES EXPRESSING NPM/ALK AND OTHER ONCOGENIC KINASES THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2009-04-09 WO claimed
EP-1963532-A2 DNA METHYLATION AS A TARGET FOR DIAGNOSIS AND TREATMENT OF CHRONIC LYMPHOCYTIC LEUKEMIA (CLL) University of Utah Research Foundation (US) 2008-09-03 EP claimed
WO-2007067695-A2 DNA METHYLATION AS A TARGET FOR DIAGNOSIS AND TREATMENT OF CHRONIC LYMPHOCYTIC LEUKEMIA (CLL) UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2007-06-14 WO claimed
US-20060127896-A1 Materials and methods for treating cancer GOH, CHRISTOPHER H K (SG) 2006-06-15 US claimed
WO-2004035045-A1 USE OF SUBSTITUTED ACRYLOLYL DISTAMYCIN DERIVATIVES IN COMBINATION WITH DEMETHYLATING AGENTS, IN THE TREATMENT OF CANCER PHARMACIA ITALIA S.P.A. (IT) 2004-04-29 WO claimed
US-20250223554-A1 METHODS AND COMPOSITIONS USING RECOMBINANT DENDRITIC CELLS FOR CANCER THERAPY RENOVARO BIOPHARMA INC. 2025-07-10 US disclosed
WO-2025056970-A1 MAMMALIAN CELL CULTURE ADDITIVES VIROCELL BIOLOGICS LTD (GB) 2025-03-20 WO disclosed
EP-0215942-A1 POLYNUCLEOTIDE ASSAY REAGENT AND METHOD. SUMMERTON JAMES 1987-04-01 EP disclosed
WO-1986005519-A1 POLYNUCLEOTIDE ASSAY REAGENT AND METHOD SUMMERTON JAMES 1986-09-25 WO disclosed
WO-1986005518-A1 STEREOREGULAR POLYNUCLEOTIDE-BINDING POLYMERS SUMMERTON JAMES 1986-09-25 WO disclosed