Doxecitine

Doxecitine

SCHEMBL10238960

Nc1ccn(C2CC(O)C(CO)O2)c(=O)n1

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 3/20 0.66
ADRB1 P08588 1/20 0.66
POLB P06746 1/20 0.62
LMNA P02545 5/20 0.62
THRB P10828 1/20 0.62
MTOR P42345 1/20 0.62
MDM2 Q00987 1/20 0.62
NCOA1 Q15788 1/20 0.62
NCOA3 Q9Y6Q9 1/20 0.62
PDE3A Q14432 4/20 0.59
CACNA1F O60840 2/20 0.59
ALB P02768 2/20 0.59
MAPT P10636 2/20 0.59
CACNA1D Q01668 2/20 0.59
CACNA1S Q13698 2/20 0.59
CACNA1C Q13936 2/20 0.59
PDE4D Q08499 2/20 0.58
SLC29A1 Q99808 1/20 0.58
P2RY2 P41231 3/20 0.51
P2RY4 P51582 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Doxecitine SCHEMBL29910618 1.00 DNMT1 (0.66) DNMT1ADRB1POLBLMNATHRB
Doxecitine SCHEMBL30616799 1.00 DNMT1 (0.66) DNMT1ADRB1POLBLMNATHRB
Doxecitine SCHEMBL15832461 1.00 DNMT1 (0.66) DNMT1ADRB1POLBLMNATHRB
Doxecitine SCHEMBL887491 1.00 DNMT1 (0.66) DNMT1ADRB1POLBLMNATHRB
Doxecitine SCHEMBL31503186 1.00 DNMT1 (0.66) DNMT1ADRB1POLBLMNATHRB
Doxecitine SCHEMBL23346798 1.00 DNMT1 (0.66) DNMT1ADRB1POLBLMNATHRB
Doxecitine SCHEMBL13700553 1.00 DNMT1 (0.66) DNMT1ADRB1POLBLMNATHRB
Doxecitine SCHEMBL23178 1.00 DNMT1 (0.66) DNMT1ADRB1POLBLMNATHRB
Doxecitine SCHEMBL193815 1.00 DNMT1 (0.66) DNMT1ADRB1POLBLMNATHRB
Doxecitine SCHEMBL2623809 1.00 DNMT1 (0.66) DNMT1ADRB1POLBLMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119235893-A Application of 2' -deoxycytidine in preparation of medicine for treating atherosclerosis 上海交通大学医学院附属瑞金医院 2025-01-03 CN claimed
US-20260097062-A1 AQUEOUS SOLUTIONS CONTAINING PURINES AND PYRIMIDINES AND USES THEREOF UCB BIOSCIENCES INC (US) 2026-04-09 US disclosed
EP-4716745-A1 NEW TLR-4 ANTAGONIST APTAMERS Merck Patent GmbH (DE) 2026-04-01 EP disclosed
EP-4704831-A2 SUBSTITUTED PYRIMIDINONE AND AZAPYRIMIDINONE COMPOUNDS, COMPOSITIONS, AND USES THEREOF Lakewood Amedex, Inc. (US) 2026-03-11 EP disclosed
US-20260066042-A1 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS OPENTRONS LABWORKS INC (US) 2026-03-05 US disclosed
US-20250367301-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING TRIPLE-NEGATIVE BREAST CANCER, COMPRISING OLIGONUCLEOTIDE AS ACTIVE INGREDIENT INTEROLIGO CORPORATION (KR) 2025-12-04 US disclosed
US-12465615-B2 Aqueous solutions containing purines and pyrimidines and uses thereof UCB BIOSCIENCES, INC. (US) 2025-11-11 US disclosed
US-12460267-B2 Compositions and methods for detection of Mycoplasma genitalium ROCHE MOLECULAR SYSTEMS, INC. (US) 2025-11-04 US disclosed
EP-4543898-A1 PYRIMIDINE NUCLEOSIDE TREATMENTS The Children's Medical Center Corporation (US) 2025-04-30 EP disclosed
WO-2025037497-A1 METHOD FOR PRODUCING SMALL INTESTINE TISSUE 国立大学法人京都大学 2025-02-20 WO disclosed
US-20100203541-A1 NUCLEOTIDE ANALOGS HELICOS BIOSCIENCES CORPORATION (US) 2010-08-12 US disclosed
US-7678894-B2 Nucleotide analogs HELICOS BIOSCIENCES CORPORATION (US) 2010-03-16 US disclosed
US-7678894-B2 Nucleotide analogs HELICOS BIOSCIENCES CORPORATION (US) 2010-03-16 US disclosed
EP-1383732-B1 LABELLING REAGENTS, METHOD FOR SYNTHESIS OF SAID REAGENTS AND METHODS FOR DETECTING BIOLOGICAL MOLECULES BIO MERIEUX (FR) 2010-02-17 EP disclosed
US-7553809-B2 Fc receptor modulators and uses thereof ILEXUS PTY LIMITED (AU) 2009-06-30 US disclosed
WO-2008144544-A1 NUCLEOTIDE ANALOGS HELICOS BIOSCIENCES CORPORATION (US) 2008-11-27 WO disclosed
US-20080286837-A1 Nucleotide analogs HELICOS BIOSCIENCES CORPORATION (US) 2008-11-20 US disclosed
US-20080286837-A1 Nucleotide analogs HELICOS BIOSCIENCES CORPORATION (US) 2008-11-20 US disclosed
US-7338805-B2 Labeling reagents, methods for synthesizing such reagents and methods for detecting biological molecules BIO MERIEUX (FR) 2008-03-04 US disclosed
US-7338805-B2 Labeling reagents, methods for synthesizing such reagents and methods for detecting biological molecules BIO MERIEUX (FR) 2008-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097062-A1 AQUEOUS SOLUTIONS CONTAINING PURINES AND PYRIMIDINES AND USES THEREOF POLG, POLRMT, TK2 DNMT1 624/4885ADRB1 4556/4885POLB 4/4885
US-20100203541-A1 NUCLEOTIDE ANALOGS NT5C2, NT5E, NUDT1 DNMT1 171/4885ADRB1 4618/4885POLB 312/4885
US-12465615-B2 Aqueous solutions containing purines and pyrimidines and uses thereof FPGS, NUDT1, POLRMT DNMT1 2147/4885ADRB1 2684/4885POLB 183/4885
US-20260066042-A1 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS POLRMT, POLL, SARS1 DNMT1 1090/4885ADRB1 2217/4885POLB 12/4885
US-20250367301-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING TRIPLE-NEGATIVE BREAST CANCER, COMPRISING OLIGONUCLEOTIDE AS ACTIVE INGREDIENT BRCA1, POLN, POLRMT DNMT1 1266/4885ADRB1 4607/4885POLB 5/4885
US-20080286837-A1 Nucleotide analogs NT5C2, NT5E, NUDT1 DNMT1 171/4885ADRB1 4618/4885POLB 312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.