Glutamine

Glutamine

SCHEMBL3178192

NC(=O)CC[C@H](N)C(=O)O.N[C@@H](CO)C(=O)O

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.83
ALOX15 P16050 1/20 0.83
BLM P54132 1/20 0.83
PMP22 Q01453 1/20 0.83
GSR P00390 2/20 0.58
SLC1A1 P43005 2/20 0.58
CYP1A2 P05177 2/20 0.58
GRM8 O00222 2/20 0.58
GRM6 O15303 2/20 0.58
GRM7 Q14831 2/20 0.58
GRM4 Q14833 2/20 0.58
GRIN2D O15399 1/20 0.58
GRIN3B O60391 1/20 0.58
GRIK1 P39086 1/20 0.58
GRM5 P41594 1/20 0.58
GRIA1 P42261 1/20 0.58
GRIA2 P42262 1/20 0.58
GRIA3 P42263 1/20 0.58
SLC1A3 P43003 1/20 0.58
SLC1A2 P43004 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamine SCHEMBL27512335 1.00 KMT2A (0.83) KMT2AALOX15BLMPMP22GSR
Glutamine SCHEMBL7559920 1.00 KMT2A (0.83) KMT2AALOX15BLMPMP22GSR
Glutamine SCHEMBL1537477 1.00 KMT2A (0.83) KMT2AALOX15BLMPMP22GSR
Glutamine SCHEMBL1537473 1.00 KMT2A (0.83) KMT2AALOX15BLMPMP22GSR
Glutamine SCHEMBL9716106 1.00 KMT2A (0.83) KMT2AALOX15BLMPMP22GSR
Glutamine SCHEMBL3178188 1.00 KMT2A (0.83) KMT2AALOX15BLMPMP22GSR
Glutamine SCHEMBL28408963 0.94 PMP22 (0.73) KMT2AALOX15BLMPMP22GSR
Glutamine SCHEMBL9716044 0.92 ALOX15 (0.70) KMT2AALOX15BLMPMP22GSR
Glutamine SCHEMBL786892 0.92 ALOX15 (0.70) KMT2AALOX15BLMPMP22GSR
Glutamine SCHEMBL7556162 0.92 ALOX15 (0.70) KMT2AALOX15BLMPMP22GSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003099322-A2 IL-11 DERIVATIVES AND THERAPEUTIC USES THEREOF ISIS INNOVATION LIMITED (GB) 2003-12-04 WO claimed
EP-0558603-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1993-09-08 EP claimed
WO-1992008688-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1992-05-29 WO claimed
US-4534881-A Inhibition of inorganic or biological CaCO3 deposition by poly amino acid derivatives UNIVERSITY OF SOUTH ALABAMA (US) 1985-08-13 US claimed
CN-110177811-B Method for protein ligation and uses thereof 奥克兰联合服务有限公司 2024-01-09 CN disclosed
US-11807671-B2 Methods for protein ligation and uses thereof AUCKLAND UNISERVICES LIMITED (NZ) 2023-11-07 US disclosed
US-20230348557-A1 T cell receptors Targeting Defective DNA Repair Proteins UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2023-11-02 US disclosed
EP-4099989-A2 T CELL RECEPTORS TARGETING DEFECTIVE DNA REPAIR PROTEINS University of Pittsburgh - Of the Commonwealth System of Higher Education (US) 2022-12-14 EP disclosed
WO-2021158962-A2 T CELL RECEPTORS TARGETING DEFECTIVE DNA REPAIR PROTEINS UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2021-08-12 WO disclosed
WO-2020072279-A2 DEUTERIUM DEPLETION MEASUREMENT COLLINS T QUE (US) 2020-04-09 WO disclosed
US-20200103396-A1 DEUTERIUM DEPLETION MEASUREMENT COLLINS T QUE (US) 2020-04-02 US disclosed
US-20190352343-A1 METHODS FOR PROTEIN LIGATION AND USES THEREOF AUCKLAND UNISERVICES LIMITED (NZ) 2019-11-21 US disclosed
WO-2004030712-A1 CONTROLLED RELEASE THERAPEUTIC WOUND DRESSINGS JOHNSON & JOHNSON MEDICAL LIMITED (GB) 2004-04-15 WO disclosed
US-6563025-B1 Nucleotide sequences coding enzymatic polypeptide for use in the generation of disease, pest and herbicide resistant plants BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2003-05-13 US disclosed
US-20020034570-A1 Cheese flavoring SYMRISE GMBH & CO. KG (DE) 2002-03-21 US disclosed
US-6319701-B1 POLYPEPTIDE; FOR USE IN THE DIAGNOSIS, PREVENTION, AND TREATMENT OF CELL PROLIFERATION, INFLAMMATION AND IMMUNE RESPONSE DEFECTS INCYTE GENOMICS, INC. 2001-11-20 US disclosed
WO-1999058640-A2 MCT-1, A HUMAN ONCOGENE PHILADELPHIA HEALTH AND EDUCATION CORPORATION (US) 1999-11-18 WO disclosed
US-5965727-A NUCLEOTIDE SEQUENCE OF PROMOTER FOR ANTHRANILATE SYNTHASE GENE FROM NICOTIANA TABACUM; FOR DIRECTING TRANSCRIPTION OF DOWNSTREAM STRUCTURAL GENES BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1999-10-12 US disclosed
EP-0929672-A1 HUMAN GTP BINDING PROTEIN GAMMA-3 INCYTE PHARMACEUTICALS, INC. (US) 1999-07-21 EP disclosed
WO-1998012325-A1 HUMAN GTP BINDING PROTEIN GAMMA-3 INCYTE PHARMACEUTICALS, INC. (US) 1998-03-26 WO disclosed