Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | ACE | P12821 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3178292 | 1.00 | APEX1 (0.70) | APEX1BLMACEPOLBTP53 | |
| SCHEMBL19119195 | 1.00 | APEX1 (0.70) | APEX1BLMACEPOLBTP53 | |
| Oxiracetam SCHEMBL2322773 | 0.83 | APEX1 (0.84) | APEX1BLMPOLBTP53TSHR | |
| Oxiracetam SCHEMBL15789330 | 0.82 | APEX1 (1.00) | APEX1BLMPOLBTP53TSHR | |
| Oxiracetam SCHEMBL2596758 | 0.82 | APEX1 (1.00) | APEX1BLMPOLBTP53TSHR | |
| SCHEMBL14426907 | 0.82 | APEX1 (0.68) | APEX1BLMPOLBTP53L3MBTL1 | |
| Oxiracetam SCHEMBL526050 | 0.82 | APEX1 (1.00) | APEX1BLMPOLBTP53TSHR | |
| SCHEMBL10582437 | 0.81 | APEX1 (0.57) | APEX1BLMPOLBTP53TSHR | |
| SCHEMBL7060207 | 0.81 | APEX1 (0.52) | APEX1BLMTP53L3MBTL1KMT2A | |
| Oxiracetam SCHEMBL15789157 | 0.81 | APEX1 (0.96) | APEX1BLMPOLBTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219540-A | Oxiracetam and key intermediate of optical isomer thereof, and preparation method and application thereof | 成都百途医药科技有限公司 | 2024-12-31 | — | — | CN | claimed |
| CN-119192049-A | Preparation method of oxiracetam impurity B | 江苏诚信药业有限公司 | 2024-12-27 | — | — | CN | claimed |
| CN-112724062-B | Preparation method of oxiracetam impurity B | 江苏诚信药业有限公司 | 2022-03-15 | — | — | CN | claimed |
| CN-109748837-B | Preparation method of 4-hydroxy-2-oxo-1-pyrrolidine acetamide | 重庆医药高等专科学校 | 2021-07-09 | — | — | CN | claimed |
| CN-112745254-A | Preparation method and application of 4-hydroxy-2-oxo-1-pyrrolidine acetic acid | 江苏诚信药业有限公司 | 2021-05-04 | — | — | CN | claimed |
| EP-0847990-A1 | 4-(C1-C4)-Alkoxy-3-pyrrolin-2-on-1-yl-acetic acid derivatives, their preparation and use in the synthesis of 4-hydroxy-2-oxo-pyrrolidin-1-yl-acetamide | LONZA AG (CH) | 1998-06-17 | — | — | EP | claimed |
| US-5371237-A | Process for the production of 4-hydroxy-2-oxopyrrolidin-1-yl-acetamide | LONZA LTD. (CH) | 1994-12-06 | — | — | US | claimed |
| US-5276164-A | Process for the production of 4-hydroxy-2-oxopyrrolidin-1-yl-acetamide | LONZA LTD. (CH) | 1994-01-04 | — | — | US | claimed |
| EP-0538505-A1 | Process for the preparation of 4-hydroxy-2-oxo-pyrrolidinyl-1-acetamide | LONZA AG (CH) | 1993-04-28 | — | — | EP | claimed |
| EP-0207681-B1 | PYRROLIDONE DERIVATIVES | ISF SOCIETA PER AZIONI (IT) | 1992-03-18 | — | — | EP | claimed |
| US-4824966-A | Process for the production of 4-hydroxy-2-oxo-pyrrolidin-1-yl acetamide | LONZA LTD. (CH) | 1989-04-25 | — | — | US | claimed |
| JP-5112525-A | — | — | None | — | — | JP | disclosed |
| CN-119219540-A | Oxiracetam and key intermediate of optical isomer thereof, and preparation method and application thereof | 成都百途医药科技有限公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-119192049-A | Preparation method of oxiracetam impurity B | 江苏诚信药业有限公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-119192049-A | Preparation method of oxiracetam impurity B | 江苏诚信药业有限公司 | 2024-12-27 | — | — | CN | disclosed |
| US-4788212-A | Pyrrolidin-2-one derivatives having nootropic activity | GIBIPHARMA S.P.A. (IT) | 1988-11-29 | — | — | US | disclosed |
| US-4703054-A | Nootropic imidazolidinones | ISF, S.P.A. (IT) | 1987-10-27 | — | — | US | disclosed |
| EP-0207680-A2 | Chemical compounds | ISF SOCIETA PER AZIONI (IT) | 1987-01-07 | — | — | EP | disclosed |
| EP-0207681-A2 | Pyrrolidone derivatives | ISF SOCIETA PER AZIONI (IT) | 1987-01-07 | — | — | EP | disclosed |
| US-4173569-A | Preparation of pyrrolidine and pyrrolidin-2-one derivatives | I.S.F. SPA (IT) | 1979-11-06 | — | — | US | disclosed |