Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.43 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628959 | 0.86 | APEX1 (0.69) | APEX1BLMTP53LMNASMN1; SMN2 | |
| SCHEMBL11107180 | 0.84 | APEX1 (0.65) | APEX1BLMTP53LMNATSHR | |
| SCHEMBL11522248 | 0.83 | APEX1 (0.58) | APEX1BLMTP53LMNASMN1; SMN2 | |
| SCHEMBL11107187 | 0.81 | APEX1 (0.54) | APEX1BLMTP53LMNA | |
| SCHEMBL3178292 | 0.81 | APEX1 (0.70) | APEX1BLMTP53SMN1; SMN2TSHR | |
| SCHEMBL19119195 | 0.81 | APEX1 (0.70) | APEX1BLMTP53SMN1; SMN2TSHR | |
| SCHEMBL3178301 | 0.81 | APEX1 (0.70) | APEX1BLMTP53SMN1; SMN2TSHR | |
| SCHEMBL9208632 | 0.80 | APEX1 (0.59) | APEX1BLMTP53LMNASMN1; SMN2 | |
| SCHEMBL9208638 | 0.80 | APEX1 (0.59) | APEX1BLMTP53LMNASMN1; SMN2 | |
| SCHEMBL353782 | 0.79 | APEX1 (0.62) | APEX1BLMTP53LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301398-A2 | Process for producing N-[(4-hydroxy-pyrrolidin-2-on-1-yl)-acetyl]-glycinamide | LONZA AG (CH) | 1989-02-01 | — | — | EP | disclosed |