SCHEMBL3178476

SCHEMBL3178476

Cc1cc(C2C3CC4CC(C3)CC2C4)ccc1-c1ccc(C2C3CC4CC(C3)CC2C4)cc1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 3/20 0.33
ESR1 P03372 2/20 0.33
CYP2C9 P11712 1/20 0.33
HSD17B1 P14061 1/20 0.33
BACE1 P56817 1/20 0.32
GABBR2 O75899 1/20 0.31
GABBR1 Q9UBS5 1/20 0.31
PAX8 Q06710 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2763439 0.77 CYP2C9 (0.41) ESR2ESR1CYP2C9LMNA
SCHEMBL27602398 0.72 KDM1A (0.48) PAX8
SCHEMBL18317396 0.69 ESR1 (0.33) ESR2ESR1CYP2C9PAX8
SCHEMBL2710584 0.69 GAA (0.42) ESR2ESR1CYP2C9
SCHEMBL2709037 0.69 KDM1A (0.33)
SCHEMBL24025385 0.69 ESR2 (0.50) ESR2ESR1CYP2C9HSD17B1
SCHEMBL18773620 0.68 S1PR1 (0.38) ESR2CYP2C9HSD17B1
SCHEMBL12769086 0.68 ESR2 (0.53) ESR2ESR1CYP2C9HSD17B1
SCHEMBL14299432 0.67 KDM1A (0.45) ESR2ESR1CYP2C9PAX8
SCHEMBL3148759 0.67 ESR2 (0.56) ESR2ESR1CYP2C9LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7652125-B2 Resin composition, polyimide resin composition, polybenzoxazole resin composition, varnish, resin film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2010-01-26 US disclosed
US-20080255335-A1 Resin Composition, Polyimide Resin Composition, Polybenzoxazole Resin Composition, Varnish, Resin Film and Semiconductor Device Using the Same SUMITOMO BAKELITE COMPANY LTD. (JP) 2008-10-16 US disclosed
EP-1813637-A1 RESIN COMPOSITION, POLYIMIDE RESIN COMPOSITION, POLY- BENZOXAZOLE RESIN COMPOSITION, VARNISHES, RESIN FILMS AND SEMICONDUCTOR DEVICES MADE BY USING THE SAME Sumitomo Bakelite Company, Limited (JP) 2007-08-01 EP disclosed