Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5005563 | 0.84 | TSHR (0.57) | TSHRHSD17B10MAPTALDH1A1LTA4H | |
| SCHEMBL20861217 | 0.84 | TSHR (0.57) | TSHRHSD17B10MAPTLTA4HCA1 | |
| SCHEMBL28792169 | 0.82 | CYP2A6 (0.55) | TSHRMAPTALDH1A1CYP2A6CA1 | |
| SCHEMBL20704784 | 0.82 | CYP2A6 (0.55) | TSHRMAPTALDH1A1CYP2A6CA1 | |
| Benzylsulfonylbenzene SCHEMBL780337 | 0.82 | TSHR (0.68) | TSHRHSD17B10MAPTALDH1A1LTA4H | |
| Benzylsulfonylbenzene SCHEMBL1877584 | 0.80 | TSHR (0.66) | TSHRHSD17B10MAPTALDH1A1LTA4H | |
| SCHEMBL4796460 | 0.78 | TSHR (0.59) | TSHRHSD17B10MAPTALDH1A1CA1 | |
| SCHEMBL14128104 | 0.78 | CYP2A6 (0.50) | MAPTALDH1A1CYP2A6CA1CA2 | |
| SCHEMBL1939695 | 0.77 | TSHR (0.62) | TSHRHSD17B10MAPTALDH1A1LTA4H | |
| SCHEMBL2921402 | 0.77 | TSHR (0.68) | TSHRHSD17B10MAPTLTA4HCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119192236-B | Serine hydrolase inhibitor and preparation method and application thereof | 西北农林科技大学深圳研究院 | 2025-03-11 | — | — | CN | disclosed |
| CN-119192236-A | Serine hydrolase inhibitor and preparation method and application thereof | 西北农林科技大学深圳研究院 | 2024-12-27 | — | — | CN | disclosed |
| EP-2526945-A1 | New CRTH2 Antagonists | Almirall, S.A. (ES) | 2012-11-28 | — | — | EP | disclosed |
| EP-2265581-A1 | COMPOUNDS HAVING CRTH2 ANTAGONIST ACTIVITY | Oxagen Limited (GB) | 2010-12-29 | — | — | EP | disclosed |
| US-20100022613-A1 | Compounds Having CRTH2 Antagonist Activity | OXAGEN LIMITED (GB) | 2010-01-28 | — | — | US | disclosed |
| WO-2009093026-A1 | COMPOUNDS HAVING CRTH2 ANTAGONIST ACTIVITY | OXAGEN LIMITED (GB) | 2009-07-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022613-A1 | Compounds Having CRTH2 Antagonist Activity | HRH2, NR3C2, HRH4 | TSHR 578/4885HSD17B10 1492/4885MAPT 4381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.