Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | DAO | P14920 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | FNTA | P49354 | 1/20 | 0.52 |
| ▸ | FNTB | P49356 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11114440 | 0.92 | MAPT (0.61) | TSHRHSD17B10DAOMAPTFNTA | |
| SCHEMBL21510835 | 0.90 | CA2 (0.55) | TSHRHSD17B10MAPTFNTAFNTB | |
| SCHEMBL11048869 | 0.90 | CA2 (0.55) | TSHRHSD17B10MAPTFNTAFNTB | |
| SCHEMBL9115481 | 0.86 | TSHR (0.51) | TSHRHSD17B10DAOMAPTFNTA | |
| Benzylsulfonylbenzene SCHEMBL780337 | 0.85 | TSHR (0.68) | TSHRHSD17B10DAOMAPTMMP2 | |
| Benzylsulfonylbenzene SCHEMBL1877584 | 0.83 | TSHR (0.66) | TSHRHSD17B10DAOMAPTMMP2 | |
| SCHEMBL11827401 | 0.81 | TSHR (1.00) | TSHRHSD17B10MAPTCA2SMN1; SMN2 | |
| SCHEMBL2919278 | 0.81 | LOX (0.51) | TSHRHSD17B10FNTAFNTBESR1 | |
| SCHEMBL2922447 | 0.81 | POLB (0.49) | TSHRHSD17B10MAPTESR1MMP2 | |
| SCHEMBL28887988 | 0.81 | MAPT (0.57) | TSHRHSD17B10MAPTESR1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222160-B1 | HALOALLYLAMINE INHIBITORS OF SSAO/VAP-1 AND USES THEREFOR | PHARMAXIS LTD (AU) | 2015-03-18 | — | — | EP | disclosed |
| US-8426587-B2 | Haloallylamine inhibitors of SSAO/VAP-1 and uses therefor | PHARMAXIS LTD. (AU) | 2013-04-23 | — | — | US | disclosed |
| CN-101917845-A | Haloallylamine inhibitors of SSAO/VAP-1 and uses therefor | PHARMAXIS LTD | 2010-12-15 | — | — | CN | disclosed |
| US-20100298330-A1 | HALOALLYLAMINE INHIBITORS OF SSAO/VAP-1 AND USES THEREFOR | PHARMAXIS LTD. (AU) | 2010-11-25 | — | — | US | disclosed |
| EP-2222160-A2 | HALOALLYLAMINE INHIBITORS OF SSAO/VAP-1 AND USES THEREFOR | Pharmaxis Ltd. (AU) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009066152-A2 | HALOALLYLAMINE INHIBITORS OF SSAO/VAP-1 AND USES THEREFOR | PHARMAXIS LTD. (US) | 2009-05-28 | — | — | WO | disclosed |
| EP-0112291-B1 | HEAT-SENSITIVE REGISTRATION MATERIAL | CIBA-GEIGY AG (CH) | 1987-01-28 | — | — | EP | disclosed |
| US-4611072-A | Heat-sensitive recording material | CIBA-GEIGY CORPORATION (US) | 1986-09-09 | — | — | US | disclosed |
| US-4536779-A | PHENOLSULFONYL SALT AS DEVELOPER FOR COLOR FORMER | CIBA-GEIGY CORPORATION (US) | 1985-08-20 | — | — | US | disclosed |
| EP-0067793-B1 | PRESSURE OR HEAT SENSITIVE RECORDING MATERIALS | CIBA-GEIGY AG (CH) | 1985-04-17 | — | — | EP | disclosed |
| EP-0112291-A2 | Heat-sensitive registration material | CIBA-GEIGY AG (CH) | 1984-06-27 | — | — | EP | disclosed |
| US-4453744-A | Pressure-sensitive or heat-sensitive recording material | CIBA-GEIGY CORPORATION (US) | 1984-06-12 | — | — | US | disclosed |
| EP-0067793-A2 | Pressure or heat sensitive recording materials | CIBA-GEIGY AG (CH) | 1982-12-22 | — | — | EP | disclosed |
| US-4125368-A | Metallized monoazo dyes | TOMS RIVER CHEMICAL CORP. (US) | 1978-11-14 | — | — | US | disclosed |
| US-4058515-A | Metallized phenyl-azo-naphthol compounds | TOMS RIVER CHEMICAL CORPORATION (US) | 1977-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298330-A1 | HALOALLYLAMINE INHIBITORS OF SSAO/VAP-1 AND USES THEREFOR | VAPA, SLC6A11, VAPB | TSHR 2000/4885HSD17B10 1500/4885DAO 662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.