Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 6/20 | 0.46 |
| ▸ | SHBG | P04278 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8731649 | 0.95 | ESR1 (0.50) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL8408018 | 0.89 | ESR1 (0.52) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL6743316 | 0.89 | ESR1 (0.62) | ESR1ESR2CYP3A4LMNAHSD17B10 | |
| SCHEMBL1691543 | 0.87 | ESR1 (0.60) | ESR1ESR2CYP3A4LMNAHSD17B10 | |
| SCHEMBL6743890 | 0.87 | ESR1 (0.60) | ESR1ESR2CYP3A4LMNAHSD17B10 | |
| SCHEMBL6744335 | 0.87 | ESR1 (0.60) | ESR1ESR2CYP3A4LMNAHSD17B10 | |
| SCHEMBL3020449 | 0.86 | ESR1 (0.70) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL3185263 | 0.84 | KIF11 (0.58) | ESR1ESR2KIF11ALDH1A1MEN1 | |
| SCHEMBL11706233 | 0.84 | KIF11 (0.51) | ESR1ESR2CYP3A4LMNAHSD17B10 | |
| SCHEMBL9164873 | 0.82 | ESR1 (0.55) | ESR1ESR2CYP3A4LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7648811-B2 | Branched polyarylene ethers and processes for the preparation thereof | XEROX CORPORATION (US) | 2010-01-19 | — | — | US | disclosed |
| US-7396895-B2 | Branched polyarylene ethers and processes for the preparation thereof | XEROX CORPORATION (US) | 2008-07-08 | — | — | US | disclosed |
| US-20080118853-A1 | BRANCHED POLYARYLENE ETHERS AND PROCESSES FOR THE PREPARATION THEREOF | XEROX CORPORATION (US) | 2008-05-22 | — | — | US | disclosed |
| US-7067608-B2 | Process for preparing branched polyarylene ethers | XEROX CORPORATION (US) | 2006-06-27 | — | — | US | disclosed |
| US-20050208416-A1 | Branched polyarylene ethers and processes for the preparation thereof | XEROX CORPORATION | 2005-09-22 | — | — | US | disclosed |
| US-20050154178-A1 | Process for preparing branched polyarylene ethers | XEROX CORPORATION | 2005-07-14 | — | — | US | disclosed |