Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 6/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | SMO | Q99835 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL318283 | 0.91 | BACE1 (0.35) | BACE1FFAR2KCNK3CNR2 | |
| SCHEMBL318277 | 0.86 | BDKRB1 (0.30) | — | |
| SCHEMBL318290 | 0.86 | KCNN4 (0.37) | KCNK3PIK3CD | |
| SCHEMBL325700 | 0.84 | CYP1A2 (0.33) | — | |
| SCHEMBL318301 | 0.82 | BACE1 (0.35) | BACE1FFAR2FAAHBACE2 | |
| SCHEMBL12187298 | 0.76 | — | — | |
| SCHEMBL521918 | 0.70 | NPSR1 (0.35) | — | |
| SCHEMBL522590 | 0.70 | NPSR1 (0.35) | — | |
| SCHEMBL521917 | 0.70 | NPSR1 (0.35) | — | |
| SCHEMBL522243 | 0.70 | NPSR1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004326-A1 | PESTICIDAL PYRROLINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2012-01-12 | — | — | WO | disclosed |
| WO-2012004326-A1 | PESTICIDAL PYRROLINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2012-01-12 | — | — | WO | disclosed |