Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.35 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL318262 | 0.82 | BACE1 (0.36) | BACE1BACE2FFAR2FAAH | |
| SCHEMBL318283 | 0.80 | BACE1 (0.35) | BACE1FFAR2 | |
| SCHEMBL319182 | 0.74 | BACE1 (0.36) | BACE1BACE2CYP11B2CYP11B1PGR | |
| SCHEMBL4751161 | 0.69 | BACE1 (0.36) | BACE1BACE2CYP11B2CYP11B1PGR | |
| SCHEMBL12187298 | 0.69 | — | — | |
| SCHEMBL12187307 | 0.69 | — | — | |
| SCHEMBL318290 | 0.67 | KCNN4 (0.37) | — | |
| SCHEMBL318277 | 0.67 | BDKRB1 (0.30) | — | |
| SCHEMBL10227531 | 0.66 | HSD17B10 (0.31) | BACE1ESR2 | |
| SCHEMBL318362 | 0.66 | BACE1 (0.36) | BACE1BACE2CYP11B2CYP11B1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004326-A1 | PESTICIDAL PYRROLINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2012-01-12 | — | — | WO | disclosed |