1,6-Hexanediol

1,6-Hexanediol

SCHEMBL3183121

OCCCCCCO.OCCCO

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.57
ALDH1A1 P00352 3/20 0.57
LMNA P02545 2/20 0.57
HSD17B10 Q99714 1/20 0.57
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
SMN1; SMN2 Q16637 2/20 0.50
GPR84 Q9NQS5 1/20 0.47
FFAR1 O14842 1/20 0.47
FFAR4 Q5NUL3 1/20 0.47
MIF P14174 1/20 0.40
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
CA12 O43570 2/20 0.36
CA9 Q16790 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CAMK2A Q9UQM7 1/20 0.35
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,5-Pentanediol SCHEMBL19547106 1.00 TSHR (0.57) TSHRALDH1A1LMNAHSD17B10MEN1
1,3-Propanediol SCHEMBL9233835 1.00 TSHR (0.57) TSHRALDH1A1LMNAHSD17B10MEN1
1,6-Hexanediol SCHEMBL10456028 1.00 TSHR (0.57) TSHRALDH1A1LMNAHSD17B10MEN1
1,5-Pentanediol SCHEMBL8846816 1.00 TSHR (0.57) TSHRALDH1A1LMNAHSD17B10MEN1
1,4-Butanediol SCHEMBL321310 0.94 SMN1; SMN2 (0.54) TSHRALDH1A1LMNAHSD17B10MEN1
SCHEMBL25302278 0.94 TSHR (0.61) TSHRALDH1A1LMNAHSD17B10MEN1
1,4-Butanediol SCHEMBL21630075 0.94 TSHR (0.61) TSHRALDH1A1LMNAHSD17B10MEN1
SCHEMBL21879690 0.94 TSHR (0.61) TSHRALDH1A1LMNAHSD17B10MEN1
SCHEMBL21462773 0.94 TSHR (0.61) TSHRALDH1A1LMNAHSD17B10MEN1
1,5-Pentanediol SCHEMBL15847271 0.94 TSHR (0.61) TSHRALDH1A1LMNAHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240191024-A1 COATINGS, ADHESIVES AND ELASTOMERS UTILISING ACETOACETATE END-CAPPED POLYOL EQUUS UK TOPCO LTD (GB) 2024-06-13 US claimed
CN-114013006-B Production method of composite floor 安徽森泰木塑科技地板有限公司 2023-11-07 CN disclosed
EP-2758033-A1 METHOD AND COMPOSITION FOR TREATING PAIN Johnson & Johnson Consumer Companies, Inc. (US) 2014-07-30 EP disclosed
US-8664352-B2 Natural oil-derived polyester polyols and polyurethanes made therefrom CARGILL, INCORPORATED (US) 2014-03-04 US disclosed
WO-2013043637-A1 METHOD AND COMPOSITION FOR TREATING PAIN JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2013-03-28 WO disclosed
US-20130072575-A1 Method and Composition for Treating Pain JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2013-03-21 US disclosed
US-20100267925-A1 NATURAL OIL-DERIVED POLYESTER POLYOLS AND POLYURETHANES MADE THEREFROM CARGILL, INCORPORATED (US) 2010-10-21 US disclosed
EP-2223995-A2 Formulas for removing paint layers and diverse dirt coatings on surfaces, method for manufacturing the agent and cleaning method Bubbles and Beyond GmbH (DE) 2010-09-01 EP disclosed