1,4-Butanediol

1,4-Butanediol

SCHEMBL321310

OCCCCO.OCCCO

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.54
TSHR P16473 4/20 0.50
ALDH1A1 P00352 3/20 0.50
LMNA P02545 2/20 0.50
HSD17B10 Q99714 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
GPR84 Q9NQS5 1/20 0.41
FFAR1 O14842 1/20 0.41
FFAR4 Q5NUL3 1/20 0.41
CAMK2A Q9UQM7 1/20 0.38
MIF P14174 1/20 0.35
CA1 P00915 3/20 0.33
CA2 P00918 3/20 0.33
CA12 O43570 2/20 0.33
CA9 Q16790 2/20 0.33
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,6-Hexanediol SCHEMBL10456028 0.94 TSHR (0.57) SMN1; SMN2TSHRALDH1A1LMNAHSD17B10
1,4-Butanediol SCHEMBL3881899 0.94 TSHR (0.56) SMN1; SMN2TSHRALDH1A1LMNAHSD17B10
1,3-Propanediol SCHEMBL9233835 0.94 TSHR (0.57) SMN1; SMN2TSHRALDH1A1LMNAHSD17B10
1,6-Hexanediol SCHEMBL3183121 0.94 TSHR (0.57) SMN1; SMN2TSHRALDH1A1LMNAHSD17B10
1,5-Pentanediol SCHEMBL8846816 0.94 TSHR (0.57) SMN1; SMN2TSHRALDH1A1LMNAHSD17B10
1,5-Pentanediol SCHEMBL19547106 0.94 TSHR (0.57) SMN1; SMN2TSHRALDH1A1LMNAHSD17B10
1,4-Butanediol SCHEMBL324322 0.94 SMN1; SMN2 (0.58) SMN1; SMN2TSHRALDH1A1LMNAHSD17B10
1,3-Propanediol SCHEMBL4973361 0.94
1,4-Butanediol SCHEMBL18642519 0.94 SMN1; SMN2 (0.58) SMN1; SMN2TSHRALDH1A1LMNAHSD17B10
1,3-Propanediol SCHEMBL8850846 0.94 TSHR (0.50) SMN1; SMN2TSHRALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3743456-A1 RIGID FOAM WITH IMPROVED INSULATING POWER Tereos Starch & Sweeteners Belgium (BE) 2020-12-02 EP claimed
WO-2019141868-A1 RIGID FOAM WITH IMPROVED INSULATING POWER TEREOS STARCH & SWEETENERS BELGIUM (BE) 2019-07-25 WO claimed
US-20170253714-A1 Sustainable Process for the Recycling of Polyethylene Phthalate SABIC GLOBAL TECHNOLOGIES, B.V. (NL) 2017-09-07 US claimed
US-9751071-B2 Continuous microwave-assisted segmented flow reactor for high-quality nanocrystal synthesis STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) 2017-09-05 US claimed
US-9623396-B2 2017-04-18 US claimed
US-20150182936-A1 CONTINUOUS MICROWAVE-ASSISTED SEGMENTED FLOW REACTOR FOR HIGH-QUALITY NANOCRYSTAL SYNTHESIS STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY 2015-07-02 US claimed
WO-2011112923-A9 POLYURETHANE POLYMERS COMPRISING COPOLYESTER POLYOLS HAVING REPEAT UNITS DERIVED FROM BIOBASED ω-HYDROXYFATTY ACIDS SYNTHEZYME LLC (US) 2012-01-12 WO claimed
EP-2268698-A1 BIODEGRADABLE POLYESTER, PREPARATION PROCESS THEREOF AND PRODUCTS COMPRISING SAID POLYESTER Novamont S.p.A. (IT) 2011-01-05 EP claimed
WO-2009118377-A1 BIODEGRADABLE POLYESTER, PREPARATION PROCESS THEREOF AND PRODUCTS COMPRISING SAID POLYESTER NOVAMONT S.P.A. (IT) 2009-10-01 WO claimed
US-20060165747-A1 Antifungal composition, method and kit for topically treating onychomycosis ROLF DAVID 2006-07-27 US claimed
US-6034202-A MIXING ACID CHLORIDE OR ACID BROMIDE SALT AND METAL ALKOXIDE ALLIEDSIGNAL INC. (US) 2000-03-07 US claimed
EP-0797640-B1 AQUEOUS COATING AGENTS BOLLIG & KEMPER GMBH & CO KG (DE) 1998-11-11 EP claimed
CN-117836044-A Defoaming agent, lubricating oil composition containing defoaming agent, and machine using lubricating oil composition DIC株式会社 2024-04-05 CN disclosed
CN-117242106-A Silicone chain-containing polymer, coating composition, resist composition, and article DIC株式会社 2023-12-15 CN disclosed
EP-4288490-A1 POLYCARBONATE POLYESTER COMPOSITION, MOLDING COMPOUND AND MOLDING BODY HAVING A GOOD IMPACT STRENGTH AND HIGH THERMAL LOADING CAPABILITY Covestro Deutschland AG (DE) 2023-12-13 EP disclosed
CN-116640293-A Epoxy ester resin, vinyl-modified epoxy ester resin, resin composition, paint, and article coated with the paint DIC株式会社 2023-08-25 CN disclosed
EP-0247870-A1 Toughened polyacetal polymer with improved wear resistance CELANESE CORPORATION (US) 1987-12-02 EP disclosed
US-4528416-A Ethylene oligomerization process carried out in a monohydric/dihydric alcohol solvent mixture SHELL OIL COMPANY (US) 1985-07-09 US disclosed
US-4447561-A POLYURETHANES BASF AKTIENGESELLSCHAFT (DE) 1984-05-08 US disclosed
US-4169196-A REMOVAL OF PEROXIDES FROM DIOL COMPONENT BY TREATMENT WITH TRIVALENT PHOSPHORUS COMPOUND PRIOR TO REACTION WITH DIISOCYANATE THE UPJOHN COMPANY (US) 1979-09-25 US disclosed