SCHEMBL3183453

SCHEMBL3183453

C=C(C)C(=O)NCN1CCOCC1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.44
TDP1 Q9NUW8 1/20 0.43
GAA P10253 1/20 0.41
RAB9A P51151 1/20 0.41
KDM4E B2RXH2 4/20 0.41
HTT P42858 1/20 0.41
LMNA P02545 1/20 0.41
HSD17B10 Q99714 2/20 0.40
TSHR P16473 2/20 0.39
ALOX15 P16050 1/20 0.39
ALDH1A1 P00352 2/20 0.39
PAOX Q6QHF9 1/20 0.39
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10278655 0.83 NPSR1 (0.52) NPSR1TDP1GAAKDM4EHTT
SCHEMBL793341 0.83 TDP1 (0.63) TDP1GAARAB9AKDM4ELMNA
SCHEMBL7105166 0.81 NPSR1 (0.50) NPSR1SMN1; SMN2TDP1GAAKDM4E
SCHEMBL14385466 0.81 NPSR1 (0.72) NPSR1SMN1; SMN2TDP1GAAKDM4E
SCHEMBL611220 0.80 GAA (0.68) TDP1GAARAB9AKDM4EHTT
SCHEMBL7615079 0.79 GAA (0.61) TDP1GAARAB9AKDM4EHTT
SCHEMBL15271453 0.79 NPSR1 (0.47) NPSR1GAAKDM4EHSD17B10ALOX15
SCHEMBL11434699 0.75 NPSR1 (0.52) NPSR1SMN1; SMN2TDP1GAAKDM4E
SCHEMBL18628076 0.74 SMN1; SMN2 (0.52) NPSR1SMN1; SMN2TDP1KDM4EHTT
SCHEMBL14665708 0.74 PAOX (0.48) NPSR1SMN1; SMN2TDP1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1052014-C Waterborne core-shell latex polymers MINNESOTA MINING & MFG (US) 2000-05-03 CN claimed
CN-117597391-A Crosslinkable acrylic modified epoxy coating compositions 阿科玛股份有限公司 2024-02-23 CN disclosed
CN-115715311-A Fast-hardening aqueous coating composition containing graft copolymer of polyamine and vinyl monomer 阿科玛股份有限公司 2023-02-24 CN disclosed
CN-107848248-B Cavitated latex particles with functionalized shell 阿科玛股份有限公司 2021-04-27 CN disclosed
CN-107848248-A Cavitated latex particles with functionalized shell 阿科玛股份有限公司 2018-03-27 CN disclosed
CN-104011087-B Use of aqueous polymer dispersions for improving the resistance to chemical influences 巴斯夫欧洲公司 2017-09-22 CN disclosed
CN-104011087-A Use of aqueous polymer dispersions for improving the resistance to chemical influences BASF SE 2014-08-27 CN disclosed
US-20120165436-A1 PIGMENT DISPERSION CONTAINING AZO PIGMENT AND AQUEOUS INK FOR INKJET RECORDING USING THE SAME FUJIFILM CORPORATION (JP) 2012-06-28 US disclosed
US-7659324-B2 Accelerators and initiators, both with polymerizable groups, can be cured without problems by radical polymerization, materials being obtained which contain an extremely small proportion of soluble components IVOCLAR VIVADENT AG (LI) 2010-02-09 US disclosed
US-7659324-B2 Accelerators and initiators, both with polymerizable groups, can be cured without problems by radical polymerization, materials being obtained which contain an extremely small proportion of soluble components IVOCLAR VIVADENT AG (LI) 2010-02-09 US disclosed
US-7659324-B2 Accelerators and initiators, both with polymerizable groups, can be cured without problems by radical polymerization, materials being obtained which contain an extremely small proportion of soluble components IVOCLAR VIVADENT AG (LI) 2010-02-09 US disclosed
EP-1574524-B1 Dental material with improved compatibility IVOCLAR VIVADENT AG (LI) 2008-10-08 EP disclosed
EP-1574524-B1 Dental material with improved compatibility IVOCLAR VIVADENT AG (LI) 2008-10-08 EP disclosed
CN-1847269-A Process for preparing aqueous dispersions of multistage emulsion polymers ROHM & HAAS (US) 2006-10-18 CN disclosed
US-20050203199-A1 Dental materials with improved compatibility IVOCLAR VIVADENT AG 2005-09-15 US disclosed
EP-1574524-A1 Dental material with improved compatibility Ivoclar Vivadent AG (LI) 2005-09-14 EP disclosed
US-4256827-A ADDITION TERPOLYMER LATEX FUJI PHOTO FILM CO., LTD. (JP) 1981-03-17 US disclosed
US-3957492-A Photographic silver halide emulsion comprising an amphoteric copolymer FUJI PHOTO FILM CO., LTD. (JA) 1976-05-18 US disclosed