Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL611220 | 0.90 | GAA (0.68) | TDP1GAAKDM4ELMNATSHR | |
| SCHEMBL7615079 | 0.89 | GAA (0.61) | TDP1GAAKDM4ELMNATSHR | |
| SCHEMBL13589552 | 0.86 | TDP1 (0.67) | TDP1GAAKDM4ELMNATSHR | |
| SCHEMBL30522606 | 0.86 | TDP1 (0.75) | TDP1GAAKDM4ELMNATSHR | |
| SCHEMBL6451721 | 0.84 | NPC1 (0.63) | TDP1KDM4ERAB9ACA12CA1 | |
| SCHEMBL7615103 | 0.83 | HDAC2 (0.49) | TDP1KDM4ETSHRCA12CA1 | |
| SCHEMBL3183453 | 0.83 | NPSR1 (0.47) | TDP1GAAKDM4ELMNATSHR | |
| SCHEMBL6913902 | 0.83 | NPC1 (0.66) | TDP1KDM4ECA12CA1CA2 | |
| SCHEMBL33262 | 0.82 | TDP1 (0.61) | TDP1GAATSHRMAPTCA12 | |
| SCHEMBL15830170 | 0.82 | CA12 (0.56) | TDP1TSHRMAPTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10551345-B2 | Poly and copoly(N-vinylamide)s and their use in capillary electrophoresis | APPLIED BIOSYSTEMS, LLC (US) | 2020-02-04 | — | — | US | claimed |
| US-20170356877-A1 | POLY AND COPOLY(N-VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS | APPLIED BIOSYSTEMS, LLC (US) | 2017-12-14 | — | — | US | claimed |
| US-9671367-B2 | Poly and copoly(N-vinylamide)s and their use in capillary electrophoresis | APPLIED BIOSYSTEMS, LLC (US) | 2017-06-06 | — | — | US | claimed |
| US-20150159009-A1 | GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS | APPLIED BIOSYSTEMS LLC (US) | 2015-06-11 | — | — | US | claimed |
| US-20140209461-A1 | Poly and Copoly(N-vinylamide)s and Their Use In Capillary Electrophoresis | APPLIED BIOSYSTEMS, LLC (US) | 2014-07-31 | — | — | US | claimed |
| US-20130153421-A1 | GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS | APPLIED BIOSYSTEMS, LLC (US) | 2013-06-20 | — | — | US | claimed |
| EP-2053067-B1 | Poly and copoly (N-vinylamide)s and their use in capillary electrophoresis | APPLIED BIOSYSTEMS LLC (US) | 2011-09-14 | — | — | EP | claimed |
| EP-2275463-A1 | Support for electrophoresis containing a composition and method | Life Technologies Corporation (US) | 2011-01-19 | — | — | EP | claimed |
| EP-1539846-B1 | GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS | LIFE TECHNOLOGIES CORP (US) | 2010-09-08 | — | — | EP | claimed |
| US-20100051461-A1 | Poly and Copolyn(N-Vinylamide)s and their use in Capillary Electrophoresis | Life Technologies Corporation (US) | 2010-03-04 | — | — | US | claimed |
| EP-1539846-A1 | GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS | Applera Corporation (US) | 2005-06-15 | — | — | EP | claimed |
| EP-1504044-A2 | CORE-SHELL POLYMERIC COMPOSITIONS | MEADWESTVACO CORPORATION, Law Department (US) | 2005-02-09 | — | — | EP | claimed |
| US-20050025741-A1 | Copolymers with (meth)acrylamides; improved separation of polynucleotides | APPLIED BIOSYSTEMS, LLC | 2005-02-03 | — | — | US | claimed |
| WO-2004104054-A1 | POLY AND COPOLY (N-VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS | APPLERA CORPORATION (US) | 2004-12-02 | — | — | WO | claimed |
| US-6767638-B2 | Core-shell polymeric compositions | MEADWESTVACO CORPORATION | 2004-07-27 | — | — | US | claimed |
| WO-2004011513-A1 | GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS | APPLERA CORPORATION (US) | 2004-02-05 | — | — | WO | claimed |
| WO-2003097709-A2 | CORE-SHELL POLYMERIC COMPOSITIONS | MEADWESTVACO CORPORATION (US) | 2003-11-27 | — | — | WO | claimed |
| US-20030215604-A1 | Core-shell polymeric compositions | WESTVACO CORPORATION (US) | 2003-11-20 | — | — | US | claimed |
| US-6423487-B2 | ACYCLIC OR HETEROCYCLIC AMINOALKYL (METH)ACRYLAMIDE POLYMERS OR POLYMERS OF (METH)ACRYLATED ALKYLENE OXIDE ADDUCTS OF PIPERAZINES OR MORPHOLINE AS VISCOSITY ENHANCERS | FUJI PHOTO FILM CO., LTD. (JP) | 2002-07-23 | — | — | US | claimed |
| US-20020015927-A1 | Thermally processed image recording material | FUJIFILM CORPORATION (JP) | 2002-02-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050025741-A1 | Copolymers with (meth)acrylamides; improved separation of polynucleotides | POLI, PCNA, POLL | TDP1 337/4885GAA 2599/4885KDM4E 3657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.