Fluoride

Fluoride

SCHEMBL3185683

Cc1cnc(C)c(C)c1.F

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 3/20 0.54
NOS2 P35228 3/20 0.54
NOS1 P29475 2/20 0.54
CCR1 P32246 3/20 0.42
CCR5 P51681 3/20 0.42
CCR8 P51685 3/20 0.42
CYP2A6 P11509 2/20 0.41
CYP1A2 P05177 1/20 0.38
HDAC6 Q9UBN7 1/20 0.36
CHRNB2 P17787 4/20 0.33
CHRNB4 P30926 4/20 0.33
CHRNA3 P32297 4/20 0.33
CHRNA4 P43681 4/20 0.33
KDM4E B2RXH2 2/20 0.33
PSMD14 O00487 1/20 0.33
COPS5 Q92905 1/20 0.33
CNR2 P34972 1/20 0.33
KMT2A Q03164 1/20 0.32
UHRF1 Q96T88 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7487 0.97
SCHEMBL29382337 0.97
SCHEMBL9784696 0.97 NOS3 (0.56) NOS3NOS2NOS1CCR1CCR5
Hydrochloric Acid SCHEMBL1936573 0.94 NOS3 (0.54) NOS3NOS2NOS1CCR1CCR5
Bromide SCHEMBL10623431 0.94 NOS3 (0.54) NOS3NOS2NOS1CCR1CCR5
Iodide SCHEMBL11070567 0.94 NOS3 (0.54) NOS3NOS2NOS1CCR1CCR5
Hydrogen Sulfide SCHEMBL5051770 0.94 NOS3 (0.54) NOS3NOS2NOS1CCR1CCR5
SCHEMBL29735919 0.94 NOS3 (0.54) NOS3NOS2NOS1CCR1CCR5
Acetonitrile SCHEMBL27689078 0.85 NOS3 (0.46) NOS3NOS2NOS1CCR1CCR5
Acetic Acid SCHEMBL11227068 0.84 NOS3 (0.45) NOS3NOS2NOS1CCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7713624-B2 Luminescent core/shell nanoparticles suitable for (F)RET-assays BAYER TECHNOLOGY SERVICES GMBH (DE) 2010-05-11 US disclosed
US-7651771-B2 Core made from luminescent metal salt selected from phosphates, sulfates or fluorides, surrounded by shell made from metal salt capable of reducing energy transfer from core after its electronic excitation to surface of nanoparticle, e.g. a shell made from non-luminescent metal salt; light generation CENTRUM FUR ANGEWANDTE NANOTECHNOLOGIE (CAN) GMBH (DE) 2010-01-26 US disclosed
EP-1431352-B1 In fluorine-containing media homogeneously dispersible nanoparticles and media containing the same CT ANGEWANDTE NANOTECH CAN (DE) 2008-04-23 EP disclosed
US-7241399-B2 Generation of preferential nanoparticles; obtain reaction mixture containing chemical intermediates, heat, recover lattice crystal of nanoparticles CENTRUM FUER ANGEWANDTE NANOTECHNOLOGIE (CAN) GMBH (DE) 2007-07-10 US disclosed
US-20070087195-A1 Core/shell nanoparticles suitable for(f)ret-assays NANOSOLUTIONS GMBH (DE) 2007-04-19 US disclosed
EP-1473348-B1 Luminescent core/shell nanoparticles CT ANGEWANDTE NANOTECH CAN (DE) 2007-03-21 EP disclosed
US-20070054120-A1 Luminescent core/shell nanoparticles CENTRUM FUR ANGEWANDTE NANOTECHNOLOGIE (CAN) GMBH (DE) 2007-03-08 US disclosed
EP-1473347-B1 Core/shell nanoparticles suitable for (F) RET-assays NANOSOLUTIONS GMBH (DE) 2006-11-29 EP disclosed
WO-2004096944-A1 CORE/SHELL NANOPARTICLES SUITABLE FOR (F)RET-ASSAYS NANOSOLUTIONS GMBH (DE) 2004-11-11 WO disclosed
WO-2004096943-A1 LUMINESCENT CORE/SHELL NANOPARTICLES NANOSOLUTIONS GMBH (DE) 2004-11-11 WO disclosed
EP-1473348-A1 Luminescent core/shell nanoparticles Nanosolutions GmbH (DE) 2004-11-03 EP disclosed
EP-1473347-A1 Core/shell nanoparticles suitable for (F) RET-assays Nanosolutions GmbH (DE) 2004-11-03 EP disclosed
EP-1431352-A1 In fluorine-containing media homogeneously dispersible nanoparticles and media containing the same Nanosolutions GmbH (DE) 2004-06-23 EP disclosed
US-20030032192-A1 Synthesis of nanoparticles CENTRUM FUR ANGEWANDTE NANOTECHNOLOGIE (CAN) GMBH (DE) 2003-02-13 US disclosed