Dimethylformamide

Dimethylformamide

SCHEMBL3188282

CN(C)C=O.C[Si](C)(C)N(C(=O)C(F)(F)F)[Si](C)(C)C

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
CHRM2 P08172 2/20 0.33
CHRM4 P08173 2/20 0.33
CHRM5 P08912 2/20 0.33
CHRM1 P11229 2/20 0.33
CHRM3 P20309 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50594 0.87 CHRM2 (0.34) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL2851398 0.80 CHRM2 (0.32) CHRM2CHRM4CHRM5CHRM1CHRM3
Trifluoroacetic Acid SCHEMBL7657198 0.72 TSHR (0.50) TSHR
Pyridine SCHEMBL5676908 0.72 TSHR (0.35) TSHR
SCHEMBL8144791 0.71
SCHEMBL23035533 0.70 CHRM2 (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL11270523 0.70 CHRM2 (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL231141 0.70 CHRM2 (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3
Dimethylformamide SCHEMBL3299693 0.69 TSHR (0.36) TSHR
Ammonia Solution, Strong SCHEMBL27574121 0.69 CHRM2 (0.32) CHRM2CHRM4CHRM5CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2041284-B1 PRODUCTION OF STILBENES AND STILBENE DERIVATIVES IN PLANT HAIRY ROOT CULTURES ARKANSAS STATE UNIV RESEARCH AND DEVELOPMENT INSTITUTE (US) 2021-05-26 EP disclosed
US-20100130623-A1 PRODUCTION OF STILBENES IN PLANT HAIRY ROOT CULTURES AND OTHER ROOT CULTURES ARKANSAS STATE UNIVERSITY RESEARCH AND DEVELOPMENT INSTITUTE (US) 2010-05-27 US disclosed
US-7666677-B2 Production of stilbenes in plant hairy root cultures ARKANSAS STATE UNIVERSITY 2010-02-23 US disclosed
EP-2041284-A2 PRODUCTION OF STILBENES AND DERIVATIVES IN PLANT HAIRY ROOT CULTURES Arkansas State University Research And Development (US) 2009-04-01 EP disclosed
WO-2008028098-A2 A NOVEL O-METHYLTRANSFERASE GENE FROM SORGHUM CLONING, EXPRESSION, TRANSFORMATION AND CHARACTERIZATION THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2008-03-06 WO disclosed
US-20080032372-A1 PRODUCTION OF STILBENES IN PLANT HAIRY ROOT CULTURES ARKANSAS STATE UNIVERSITY RESEARCH AND DEVELOPMENT INSTITUTE (US) 2008-02-07 US disclosed
WO-2008005988-A2 PRODUCTION OF STILBENES AND DERIVATIVES IN PLANT HAIRY ROOT CULTURES ARKANSAS STATE UNIVERSITY RESEARCH AND DEVELOPMENT INSTITUTE (US) 2008-01-10 WO disclosed