Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 2/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL15302675 | 0.91 | TSHR (0.41) | TSHRCYP2C19TDP1 | |
| Trifluoroacetic Acid SCHEMBL3591146 | 0.82 | ALDH1A1 (0.39) | TSHRALDH1A1CYP2C19L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL30002497 | 0.81 | CES1 (0.31) | TSHRALDH1A1CYP2C19TDP1 | |
| Dimethylformamide SCHEMBL18548326 | 0.80 | TSHR (0.41) | TSHRALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL29819862 | 0.79 | TSHR (0.40) | TSHRALDH1A1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL27529311 | 0.79 | ALDH1A1 (0.37) | TSHRALDH1A1CYP2C19L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL28243137 | 0.79 | TSHR (0.45) | TSHR | |
| Dimethylformamide SCHEMBL9754300 | 0.78 | — | — | |
| Dimethylformamide SCHEMBL28869383 | 0.78 | — | — | |
| Trifluoroacetic Acid SCHEMBL1628375 | 0.76 | ALDH1A1 (0.36) | TSHRALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109261130-A | Amino-terminated hyperbranched polymer grafted chitosan microsphere formaldehyde adsorbent and preparation method thereof | 南京工业大学 | 2019-01-25 | — | — | CN | disclosed |
| CN-109045032-A | Aminopyridines and application method | 麦迪威森技术有限责任公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-106132950-B | Aminopyridines and methods of use | 麦迪威森技术有限责任公司 | 2018-11-09 | — | — | CN | disclosed |
| CN-106188043-A | Tetracyclic compound | 梅迪维新技术公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-106132950-A | Compounds and methods of use | 麦迪韦逊技术股份有限公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-106029072-A | Heterocyclic compounds and methods of use | 麦迪韦逊技术股份有限公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-103476416-B | The Compounds and methods for for the treatment of hypertension | 梅迪维新技术公司 | 2016-09-21 | — | — | CN | disclosed |
| US-8613865-B2 | Amidium-based ionic liquids for carbon dioxide absorption | HYUNDAI MOTOR COMPANY (KR) | 2013-12-24 | — | — | US | disclosed |
| US-20130012699-A1 | AMIDIUM-BASED IONIC LIQUIDS FOR CARBON DIOXIDE ABSORPTION | KIA MOTORS CORPORATION (KR) | 2013-01-10 | — | — | US | disclosed |
| US-8282710-B2 | Amidium-based ionic liquids for carbon dioxide absorption | HYUNDAI MOTOR COMPANY (KR) | 2012-10-09 | — | — | US | disclosed |
| CN-101983059-A | New 2,3,4,5-terahydro-1h-pyrido[ 4,3-b] indole compounds and methods of use thereof | MEDIVATION TECHNOLOGIES INC | 2011-03-02 | — | — | CN | disclosed |
| US-6358960-B1 | FOR THERAPY OF INTRAVASCULAR COAGULATION, CORONARY THROMBOSIS, CEREBRAL INFARCTION, CEREBRAL EMBOLISM, TRANSIENT ISCHEMIC ATTACK, CEREBROVASCULAR DISORDERS, PULMONARY VASCULAR DISEASES, DEEP VENOUS THROMBOSIS, ETC. | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| CN-1266432-A | Bis-pyridocycloheptane compounds useful for inhibition of farnesyl protein transferase | SCHERING CORP (US) | 2000-09-13 | — | — | CN | disclosed |
| CN-1248253-A | Compounds for inhibition of farnesyl protein transferase | SCHERING CORP (US) | 2000-03-22 | — | — | CN | disclosed |
| CN-1237164-A | compounds useful as farnesyl-protein transferase inhibitors | SCHERING CORP (US) | 1999-12-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012699-A1 | AMIDIUM-BASED IONIC LIQUIDS FOR CARBON DIOXIDE ABSORPTION | SLC7A5, SLC1A5, SLC7A1 | TSHR 2842/4885ALDH1A1 3579/4885CYP2C19 1445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.