Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.72 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.52 |
| ▸ | UBE2M | P61081 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3188296 | 1.00 | EPHX2 (0.72) | EPHX2NPC1RAB9ADCUN1D1UBE2M | |
| SCHEMBL3183175 | 0.89 | EPHX2 (0.66) | EPHX2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3183168 | 0.89 | EPHX2 (0.66) | EPHX2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3182153 | 0.89 | EPHX2 (0.74) | EPHX2NPC1RAB9ADCUN1D1UBE2M | |
| SCHEMBL3182145 | 0.89 | EPHX2 (0.74) | EPHX2NPC1RAB9ADCUN1D1UBE2M | |
| SCHEMBL3178477 | 0.88 | EPHX2 (0.72) | EPHX2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3178470 | 0.88 | EPHX2 (0.72) | EPHX2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3190106 | 0.88 | EPHX2 (0.69) | EPHX2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL12932322 | 0.88 | EPHX2 (0.69) | EPHX2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3181043 | 0.87 | EPHX2 (0.72) | EPHX2NPC1RAB9ADCUN1D1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662910-B2 | Inhibitors for the soluble epoxide hydrolase | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-02-16 | — | — | US | claimed |