SCHEMBL3188486

SCHEMBL3188486

NC(=O)N(N)Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 1/20 0.50
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
CA12 O43570 1/20 0.47
CA9 Q16790 1/20 0.47
KDM4E B2RXH2 1/20 0.46
LMNA P02545 1/20 0.46
CA2 P00918 1/20 0.45
ALDH1A1 P00352 3/20 0.44
NPSR1 Q6W5P4 1/20 0.44
PLA2G10 O15496 1/20 0.44
PLA2G2A P14555 1/20 0.44
TSHR P16473 2/20 0.43
GLA P06280 1/20 0.43
HTT P42858 1/20 0.43
PAX8 Q06710 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
AKR1B1 P15121 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27460406 0.98 AOC3 (0.48) AOC3NPC1RAB9ACA12CA9
SCHEMBL258776 0.86 AOC3 (0.54) AOC3NPC1RAB9ACA12CA9
Hydrazine SCHEMBL8651254 0.84 AOC3 (0.52) AOC3NPC1RAB9ACA12CA9
SCHEMBL29851956 0.84 AOC3 (0.52) AOC3NPC1RAB9ACA12CA9
SCHEMBL11693547 0.84 NPC1 (0.53) AOC3NPC1RAB9ACA12CA9
Hydrochloric Acid SCHEMBL10536523 0.84 AOC3 (0.52) AOC3NPC1RAB9ACA12CA9
SCHEMBL10782311 0.83 NPC1 (0.48) AOC3NPC1RAB9ACA12CA9
SCHEMBL1920895 0.83 AOC3 (0.50) AOC3NPC1RAB9ACA12CA9
SCHEMBL18536773 0.82 AOC3 (0.45) AOC3NPC1RAB9ACA12CA9
SCHEMBL10416109 0.81 AOC3 (0.54) AOC3NPC1RAB9ACA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1353986-B1 COLORED THERMOPLASTIC RESIN COMPOSITIONS FOR LASER WELDING, ANTHRAQUINONE COLORANTS THEREFOR AND MOLDED PRODUCT THEREFROM DU PONT (US) 2006-04-12 EP claimed
EP-1334148-B1 COLORED THERMOPLASTIC RESIN COMPOSITIONS FOR LASER WELDING, COLORANTS THEREFOR OF MIXTURES OF AMINE SALTS OF ANTHRAQUINONE AND MONOAZO COMPLEX DYES, AND MOLDED PRODUCT THEREFROM DU PONT (US) 2006-03-15 EP claimed
EP-0518655-B1 Solid phase peptide synthesis ZENECA LTD (GB) 1997-09-10 EP claimed
US-5602231-A SOLID PHASE SYNTHESIS OF PEPTIDES CONTAINING A C-TERMINAL AZA-AMINO ACID ZENECA LIMITED (GB) 1997-02-11 US claimed
EP-0518655-A2 Solid phase peptide synthesis ZENECA LIMITED (GB) 1992-12-16 EP claimed
US-12545683-B2 CBP/catenin signaling pathway inhibitors and uses thereof 3+2 PHARMA, LLC (US) 2026-02-10 US disclosed
US-20230348476-A1 CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF 3 2 PHARMA LLC (US) 2023-11-02 US disclosed
US-11655253-B2 CBP/catenin signaling pathway inhibitors and uses thereof 3+2 PHARMA, LLC (US) 2023-05-23 US disclosed
CN-115835865-A CBP/catenin signal transmission path inhibitor and application thereof 3+2 制药有限责任公司 2023-03-21 CN disclosed
EP-4117663-A1 CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF 3+2 Pharma LLC (US) 2023-01-18 EP disclosed
US-20210317123-A1 CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF 3+2 PHARMA, LLC 2021-10-14 US disclosed
WO-2021183796-A1 CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF 3+2 PHARMA (US) 2021-09-16 WO disclosed
EP-1646633-A1 BETA-STRAND MIMETICS AND METHOD RELATING THERETO Choongwae Pharma Corporation (KR) 2006-04-19 EP disclosed
EP-1353986-B1 COLORED THERMOPLASTIC RESIN COMPOSITIONS FOR LASER WELDING, ANTHRAQUINONE COLORANTS THEREFOR AND MOLDED PRODUCT THEREFROM DU PONT (US) 2006-04-12 EP disclosed
EP-1334148-B1 COLORED THERMOPLASTIC RESIN COMPOSITIONS FOR LASER WELDING, COLORANTS THEREFOR OF MIXTURES OF AMINE SALTS OF ANTHRAQUINONE AND MONOAZO COMPLEX DYES, AND MOLDED PRODUCT THEREFROM DU PONT (US) 2006-03-15 EP disclosed
CN-1244620-C Colored thermoplastic resin compositions for laser welding, anthraquinone colorants therefor and molded product therefrom DU PONT (US) 2006-03-08 CN disclosed
WO-2004108731-A1 BETA-STRAND MIMETICS AND METHOD RELATING THERETO CHOONGWAE PHARMA CORPORATION (KR) 2004-12-16 WO disclosed
US-20040053331-A1 Beta-strand mimetics and method relating thereto CHOONGWAE PHARMA CORPORATION (KR) 2004-03-18 US disclosed
CN-1474850-A Colored thermoplastic resin compositions for laser welding, anthraquinone colorants therefor and molded product therefrom ��Ļ���Ű˾ 2004-02-11 CN disclosed
US-3984463-A Herbicidal 2-phenyl semicarbazides SHELL OIL COMPANY (US) 1976-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348476-A1 CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF CREBBP, CREB1, EP300 AOC3 4804/4885NPC1 1730/4885RAB9A 2899/4885
US-20040053331-A1 Beta-strand mimetics and method relating thereto BIRC5, BIRC7, XIAP AOC3 4511/4885NPC1 4373/4885RAB9A 3852/4885
US-12545683-B2 CBP/catenin signaling pathway inhibitors and uses thereof CREBBP, CREB1, CTNNB1 AOC3 4563/4885NPC1 1535/4885RAB9A 2198/4885
US-11655253-B2 CBP/catenin signaling pathway inhibitors and uses thereof CREBBP, CREB1, EP300 AOC3 4804/4885NPC1 1730/4885RAB9A 2899/4885
US-20210317123-A1 CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF CREBBP, CREB1, EP300 AOC3 4804/4885NPC1 1730/4885RAB9A 2899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.