Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL318968 | 0.96 | BACE1 (0.34) | P2RX7BACE1BACE2TRPV1DDR1 | |
| SCHEMBL318197 | 0.88 | EPHX2 (0.37) | P2RX7DDR1PTGES | |
| SCHEMBL327465 | 0.88 | TRPV1 (0.35) | P2RX7TRPV1ALDH1A1ADORA3ADORA2A | |
| SCHEMBL318389 | 0.86 | EPHX2 (0.33) | P2RX7DDR1PTGES | |
| SCHEMBL318969 | 0.81 | MAPT (0.37) | HTTMTORALDH1A1ADORA3ADORA2A | |
| SCHEMBL319713 | 0.79 | EPHX2 (0.37) | P2RX7DDR1PTGES | |
| SCHEMBL318073 | 0.79 | EPHX2 (0.35) | P2RX7ALDH1A1 | |
| SCHEMBL318019 | 0.78 | EPHX2 (0.40) | — | |
| SCHEMBL854897 | 0.78 | RXRA (0.31) | RXRARXRBRXRG | |
| SCHEMBL926057 | 0.78 | EPHX2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004326-A1 | PESTICIDAL PYRROLINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2012-01-12 | — | — | WO | disclosed |