⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4924782 | 0.76 | — | — | |
| SCHEMBL8941078 | 0.74 | — | — | |
| SCHEMBL907735 | 0.74 | — | — | |
| SCHEMBL1859032 | 0.74 | — | — | |
| SCHEMBL6661278 | 0.74 | — | — | |
| SCHEMBL452030 | 0.74 | — | — | |
| SCHEMBL596463 | 0.74 | — | — | |
| SCHEMBL4922063 | 0.74 | — | — | |
| SCHEMBL3135272 | 0.74 | — | — | |
| SCHEMBL4930532 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 316 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024115549-A1 | ARYL- AND HETEROARYL-SULFONAMIDE DERIVATIVES AS CCR8 MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-06-06 | — | — | WO | claimed |
| WO-2015197188-A1 | PYRAZOLYL-BASED CARBOXAMIDES AS CRAC INHIBITORS | Grünenthal GmbH (DE) | 2015-12-30 | — | — | WO | claimed |
| WO-2015197187-A1 | PYRAZOLYL-BASED CARBOXAMIDES V | Grünenthal GmbH (DE) | 2015-12-30 | — | — | WO | claimed |
| EP-2918580-A1 | PIPERAZINEDIONES AS OXYTOCIN RECEPTOR ANTAGONISTS | Glaxo Group Limited (GB) | 2015-09-16 | — | — | EP | claimed |
| WO-2015090579-A1 | PYRAZOLYL-BASED CARBOXAMIDES IV | Grünenthal GmbH (DE) | 2015-06-25 | — | — | WO | claimed |
| WO-2015090580-A1 | PYRAZOLYL-BASED CARBOXAMIDES USEFUL AS CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL (ICRAC) INHIBITORS | Grünenthal GmbH (DE) | 2015-06-25 | — | — | WO | claimed |
| US-20150166505-A1 | PYRIDINYL-SUBSTITUTED PYRAZOLYL CARBOXAMIDES | Grünenthal GmbH (DE) | 2015-06-18 | — | — | US | claimed |
| US-8742099-B2 | Compounds | GLAXO GROUP LIMITED (GB) | 2014-06-03 | — | — | US | claimed |
| CN-101495464-B | Prokineticin 1 receptor antagonists | JANSSEN PHARMACEUTICA NV | 2014-03-05 | — | — | CN | claimed |
| CN-103396398-A | Prokineticin 1 receptor antagonists | JANSSEN PHARMACEUTICA NV | 2013-11-20 | — | — | CN | claimed |
| WO-1999038868-A1 | AZOLO TRIAZINES AND PYRIMIDINES | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-08-05 | — | — | WO | claimed |
| EP-0112707-B1 | AMINOPYRIMIDINONE DERIVATIVES AS HISTAMINE H1-ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1987-11-04 | — | — | EP | claimed |
| EP-0134091-B1 | PYRIMIDONE DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1987-06-16 | — | — | EP | claimed |
| US-4665078-A | RHINITIS, HAY FEVER, ASTHMA, ECZEMA | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1987-05-12 | — | — | US | claimed |
| EP-0068833-B1 | PYRIMIDINONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-10-15 | — | — | EP | claimed |
| US-4548940-A | Pyridylaminoalkylaminopyrimidones useful as histamine H1 -antagonists | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1985-10-22 | — | — | US | claimed |
| EP-0134091-A1 | Pyrimidone derivatives | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1985-03-13 | — | — | EP | claimed |
| US-4486434-A | PYRIDYLALKYLAMINO PYRIDYLMETHYL PYRIMIDONES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1984-12-04 | — | — | US | claimed |
| EP-0112707-A2 | Aminopyrimidinone derivatives as histamine H1-antagonists | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1984-07-04 | — | — | EP | claimed |
| EP-0068833-A2 | Pyrimidinone derivatives and pharmaceutical compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1983-01-05 | — | — | EP | claimed |