⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL318966 | 0.74 | — | — | |
| SCHEMBL4924782 | 0.72 | — | — | |
| SCHEMBL8941078 | 0.70 | — | — | |
| SCHEMBL4922063 | 0.70 | — | — | |
| SCHEMBL1637915 | 0.67 | — | — | |
| SCHEMBL4796172 | 0.67 | UHRF1 (0.30) | — | |
| SCHEMBL4927303 | 0.67 | — | — | |
| SCHEMBL1859032 | 0.65 | — | — | |
| SCHEMBL4926885 | 0.64 | KDM4E (0.30) | — | |
| SCHEMBL4922415 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004011471-A1 | PROCESS FOR THE PREPARATION OF CEPHEM ESTERS | RANBAXY LABORATORIES LIMITED (IN) | 2004-02-05 | — | — | WO | claimed |
| EP-2723882-B1 | PROCESS FOR PREPARING 3'-THIOSUBSTITUTED CEPHALOSPORINS EMPLOYING A PENICILLIN G ACYLASE | CENTRIENT PHARMACEUTICALS NETHERLANDS B V (NL) | 2019-05-01 | — | — | EP | disclosed |
| US-20150112057-A1 | NOVEL CRYSTALLINE CEFOPERAZONE INTERMEDIATE | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2015-04-23 | — | — | US | disclosed |
| EP-2723882-A1 | PROCESS FOR PREPARING 3'-THIOSUBSTITUTED CEPHALOSPORINS EMPLOYING A PENICILLIN G ACYLASE | DSM Sinochem Pharmaceuticals Netherlands B.V. (NL) | 2014-04-30 | — | — | EP | disclosed |
| EP-2723881-A2 | NOVEL CRYSTALLINE CEFOPERAZONE INTERMEDIATE | DSM Sinochem Pharmaceuticals Netherlands B.V. (NL) | 2014-04-30 | — | — | EP | disclosed |
| WO-2012175585-A1 | PROCESS FOR PREPARING 3'-THIOSUBSTITUTED CEPHALOSPORINS EMPLOYING A PENICILLIN G ACYLASE | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2012-12-27 | — | — | WO | disclosed |
| WO-2012175587-A2 | NOVEL CRYSTALLINE CEFOPERAZONE INTERMEDIATE | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2012-12-27 | — | — | WO | disclosed |
| WO-2004011471-A1 | PROCESS FOR THE PREPARATION OF CEPHEM ESTERS | RANBAXY LABORATORIES LIMITED (IN) | 2004-02-05 | — | — | WO | disclosed |