SCHEMBL3190169

SCHEMBL3190169

CC(C)(C)OC(=O)COc1cccc(OCC(=O)OC(C)(C)C)c1S(OS(=O)(=O)c1c(F)c(F)c(F)c(F)c1F)(c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACLY P53396 4/20 0.36
MAPT P10636 2/20 0.36
POLB P06746 2/20 0.36
HPGD P15428 2/20 0.36
DDB1 Q16531 1/20 0.36
CRBN Q96SW2 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
PSEN1 P49768 2/20 0.35
PSEN2 P49810 2/20 0.35
APH1B Q8WW43 2/20 0.35
NCSTN Q92542 2/20 0.35
APH1A Q96BI3 2/20 0.35
PSENEN Q9NZ42 2/20 0.35
PTPN1 P18031 1/20 0.35
LMNA P02545 1/20 0.32
KAT6A Q92794 1/20 0.32
ALOX5AP P20292 1/20 0.32
FEN1 P39748 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3189163 0.92 ACLY (0.36) ACLYMAPTPOLBHPGDDDB1
SCHEMBL3191613 0.91 MAPT (0.45) ACLYMAPTPOLBHPGDCYP2C9
SCHEMBL3192050 0.89 ACLY (0.36) ACLYMAPTPOLBHPGDDDB1
SCHEMBL3201825 0.88 ACLY (0.39) ACLYMAPTPOLBHPGDDDB1
SCHEMBL8645077 0.86 PSEN1 (0.44) MAPTPOLBHPGDCYP2C9CYP2C19
SCHEMBL3199694 0.86 ACLY (0.36) ACLYMAPTPOLBHPGDDDB1
SCHEMBL8644652 0.85 PSEN1 (0.40) ACLYMAPTPOLBHPGDCYP2C9
SCHEMBL3193670 0.85 MAPT (0.41) ACLYMAPTPOLBHPGDCYP2C9
SCHEMBL3203236 0.85 PSEN1 (0.40) ACLYMAPTPOLBHPGDCYP2C9
SCHEMBL3188782 0.85 PSEN1 (0.42) ACLYHPGDCYP2C9CYP2C19PSEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206888-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2012-06-26 US disclosed
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
EP-1953593-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2008-08-06 EP disclosed
US-7060414-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-06-13 US disclosed
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed