Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.60 |
| ▸ | HPGD | P15428 | 10/20 | 0.60 |
| ▸ | RAB9A | P51151 | 10/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.60 |
| ▸ | TP53 | P04637 | 7/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.56 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 1/20 | 0.48 |
| ▸ | CCR8 | P51685 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27760788 | 0.85 | RAB9A (0.52) | NPC1ALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL14939052 | 0.83 | NPC1 (0.64) | NPC1ALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL5832164 | 0.82 | NPC1 (0.62) | NPC1ALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL805832 | 0.80 | NPC1 (0.60) | NPC1ALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL21674269 | 0.80 | NPC1 (0.63) | NPC1ALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL24155569 | 0.80 | NPC1 (0.60) | NPC1ALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL25011928 | 0.79 | NPC1 (0.58) | NPC1ALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL26023364 | 0.79 | NPC1 (0.58) | NPC1ALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL29531707 | 0.78 | NPC1 (0.69) | NPC1ALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL824375 | 0.78 | NPC1 (0.69) | NPC1ALDH1A1HPGDRAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105754590-B | Methyl-substituted benzoxazolyl cuprous pyridine complex yellow phosphor material | 中国计量大学 | 2017-04-26 | — | — | CN | claimed |
| CN-104892645-A | Cuprous complex phosphor material of methyl substitution benzoxazolyl pyridine | UNIV JILIANG CHINA | 2015-09-09 | — | — | CN | claimed |
| US-7670591-B2 | Heteroaryl substituted benzoxazoles | ASTRAZENECA AB (SE) | 2010-03-02 | — | — | US | claimed |
| EP-2035418-A1 | NOVEL HETEROARYL SUBSTITUTED BENZOXAZOLES | Astra Zeneca AB (SE) | 2009-03-18 | — | — | EP | claimed |
| US-20080027051-A1 | Novel Heteroaryl Substituted Benzoxazoles | ASTRAZENECA AB (SE) | 2008-01-31 | — | — | US | claimed |
| WO-2007149030-A1 | NOVEL HETEROARYL SUBSTITUTED BENZOXAZOLES | ASTRAZENECA AB (SE) | 2007-12-27 | — | — | WO | claimed |
| WO-2021230512-A1 | BENZAZOLE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | 주식회사 랩토 | 2021-11-18 | — | — | WO | disclosed |
| CN-105754590-B | Methyl-substituted benzoxazolyl cuprous pyridine complex yellow phosphor material | 中国计量大学 | 2017-04-26 | — | — | CN | disclosed |
| CN-105754590-B | Methyl-substituted benzoxazolyl cuprous pyridine complex yellow phosphor material | 中国计量大学 | 2017-04-26 | — | — | CN | disclosed |
| CN-105754590-A | Methyl-substituted benzoxazolyl cuprous pyridine complex yellow phosphor material | 中国计量大学 | 2016-07-13 | — | — | CN | disclosed |
| CN-105713021-A | Methyl-substituted benzoxazolyl pyridine cuprous complex yellow/green phosphorescent material | 中国计量大学 | 2016-06-29 | — | — | CN | disclosed |
| CN-104892645-A | Cuprous complex phosphor material of methyl substitution benzoxazolyl pyridine | UNIV JILIANG CHINA | 2015-09-09 | — | — | CN | disclosed |
| CN-104892645-A | Cuprous complex phosphor material of methyl substitution benzoxazolyl pyridine | UNIV JILIANG CHINA | 2015-09-09 | — | — | CN | disclosed |
| CN-101506201-A | Novel heteroaryl substituted benzoxazoles | ASTRAZENECA AB (SE) | 2009-08-12 | — | — | CN | disclosed |
| EP-2035418-A1 | NOVEL HETEROARYL SUBSTITUTED BENZOXAZOLES | Astra Zeneca AB (SE) | 2009-03-18 | — | — | EP | disclosed |
| US-20080027051-A1 | Novel Heteroaryl Substituted Benzoxazoles | ASTRAZENECA AB (SE) | 2008-01-31 | — | — | US | disclosed |
| US-20080027051-A1 | Novel Heteroaryl Substituted Benzoxazoles | ASTRAZENECA AB (SE) | 2008-01-31 | — | — | US | disclosed |
| US-20080027051-A1 | Novel Heteroaryl Substituted Benzoxazoles | ASTRAZENECA AB (SE) | 2008-01-31 | — | — | US | disclosed |
| WO-2007149030-A1 | NOVEL HETEROARYL SUBSTITUTED BENZOXAZOLES | ASTRAZENECA AB (SE) | 2007-12-27 | — | — | WO | disclosed |
| WO-2007149030-A1 | NOVEL HETEROARYL SUBSTITUTED BENZOXAZOLES | ASTRAZENECA AB (SE) | 2007-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027051-A1 | Novel Heteroaryl Substituted Benzoxazoles | PSEN1, PSEN2, APP | NPC1 293/4885ALDH1A1 1812/4885HPGD 1802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.