SCHEMBL319203

SCHEMBL319203

CCCCOC(=O)c1ccc(C=C(C)C(N)=O)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.60
LMNA P02545 3/20 0.60
CYP1A2 P05177 3/20 0.60
CYP2C19 P33261 2/20 0.60
CYP3A4 P08684 2/20 0.60
CYP2C9 P11712 1/20 0.60
PDE4D Q08499 1/20 0.60
ESR1 P03372 6/20 0.57
CYP2D6 P10635 2/20 0.57
MAPK1 P28482 1/20 0.57
NR1H2 P55055 1/20 0.57
RNASEL Q05823 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
HPGD P15428 1/20 0.55
RECQL P46063 1/20 0.55
MAPT P10636 2/20 0.54
ALDH1A1 P00352 2/20 0.54
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54
STS P08842 7/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL319202 1.00 TSHR (0.60) TSHRLMNACYP1A2CYP2C19CYP3A4
SCHEMBL17152668 0.87 ESR1 (0.59) TSHRLMNACYP1A2CYP2C19CYP3A4
SCHEMBL2567047 0.85 LMNA (0.56) TSHRLMNACYP1A2CYP3A4ESR1
SCHEMBL2567045 0.85 LMNA (0.56) TSHRLMNACYP1A2CYP3A4ESR1
SCHEMBL11864509 0.81 ESR1 (0.70) TSHRLMNACYP1A2CYP2C19CYP3A4
SCHEMBL11864516 0.81 ESR1 (0.70) TSHRLMNACYP1A2CYP2C19CYP3A4
SCHEMBL37476 0.80 ESR1 (0.85) TSHRLMNACYP1A2CYP2C19CYP3A4
SCHEMBL9099239 0.79 ESR1 (0.68) TSHRLMNACYP1A2CYP2C19CYP3A4
SCHEMBL6896936 0.79 TSHR (0.75) TSHRLMNACYP1A2CYP2C19CYP3A4
Hydrogen Peroxide SCHEMBL28645617 0.78 ESR1 (0.82) TSHRLMNACYP1A2CYP2C19CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023094549-A1 FLEXIBLE PRESSURE-SENSITIVE ADHESIVES HAVING IMPROVED PROPERTIES WESTFÄLISCHE HOCHSCHULE GELSENKIRCHEN BOCHOLT RECKLINGHAUSEN (DE) 2023-06-01 WO disclosed
US-10889146-B2 Tire object provided with an elastomer layer made of a thermoplastic elastomer in the form of an (A-b-(a-methylstyrene-co-B))n-b-C block copolymer COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2021-01-12 US disclosed
EP-2927253-B1 ORGANOPOLYSILOXANE GRAFT POLYMER KAO CORP (JP) 2018-09-12 EP disclosed
US-10030131-B2 Pneumatic object provided with a gastight layer containing a thermoplastic elastomer and a thermoplastic COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2018-07-24 US disclosed
EP-2791238-B1 TYRE PROVIDED WITH AN OUTER SIDEWALL COMPRISING A MIXTURE OF A DIENE ELASTOMER AND A THERMOPLASTIC ELASTOMER MICHELIN & CIE (FR) 2018-06-06 EP disclosed
EP-2791236-B1 TYRE PROVIDED WITH AN INNER LAYER COMPRISING A MIXTURE OF A DIENE ELASTOMER AND A THERMOPLASTIC ELASTOMER MICHELIN & CIE (FR) 2018-05-02 EP disclosed
US-9914328-B2 Inflatable object provided with a gas-tight layer containing a thermoplastic elastomer and a hydrocarbon-based resin COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (CH) 2018-03-13 US disclosed
US-20180043734-A1 TIRE OBJECT PROVIDED WITH AN ELASTOMER LAYER MADE OF A THERMOPLASTIC ELASTOMER IN THE FORM OF AN (A-B-(A-METHYLSTYRENE-CO-B))N-B-C BLOCK COPOLYMER COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2018-02-15 US disclosed
EP-3268401-A1 TYRE OBJECT PROVIDED WITH AN ELASTOMER LAYER MADE OF A THERMOPLASTIC ELASTOMER IN THE FORM OF AN (A-B(A-CO-B))N-B-C BLOCK COPOLYMER Compagnie Générale des Etablissements Michelin (FR) 2018-01-17 EP disclosed
CN-104797412-B Including the pneumatic tire of rubber liner that bonded by fiber module and its manufacture method 米其林集团总公司 2017-03-08 CN disclosed
WO-2000040403-A1 WATER-BASED, HEAT SEALABLE ADHESIVE FOR LAMINATING DECORATIVE PANELS ATO FINDLEY, INC. (US) 2000-07-13 WO disclosed
EP-0910351-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. Searle & Co. (US) 1999-04-28 EP disclosed
EP-0481333-B1 A silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1998-08-12 EP disclosed
WO-1997049387-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed
EP-0426043-B1 Silver halide color photographic material and method for forming color image FUJI PHOTO FILM CO LTD (JP) 1996-01-24 EP disclosed
US-5352571-A Having triazdopyrrole type cyan coupler and sparingly water soluble polymer FUJI PHOTO FILM CO., LTD. (JP) 1994-10-04 US disclosed
US-5264332-A Color print paper, improved formation of cyan dye image FUJI PHOTO FILM CO., LTD. (JP) 1993-11-23 US disclosed
EP-0481333-A1 A silver halide color photographic material Fuji Photo Film Co., Ltd. (JP) 1992-04-22 EP disclosed
US-5082764-A High boiling organic solven, cyan coupler, diffusion resistant substituted hydroquinone or benzoquinone FUJI PHOTO FILM CO., LTD. (JP) 1992-01-21 US disclosed
EP-0426043-A2 Silver halide color photographic material and method for forming color image Fuji Photo Film Co., Ltd. (JP) 1991-05-08 EP disclosed