⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL597798 | 1.00 | MAPK10 (0.38) | — | |
| SCHEMBL28384192 | 0.97 | MAPK10 (0.37) | — | |
| Water SCHEMBL261457 | 0.97 | MAPK10 (0.37) | — | |
| SCHEMBL1936955 | 0.97 | MAPK10 (0.37) | — | |
| SCHEMBL8402032 | 0.81 | — | — | |
| SCHEMBL8537626 | 0.81 | — | — | |
| SCHEMBL11006695 | 0.74 | — | — | |
| SCHEMBL12130697 | 0.74 | — | — | |
| SCHEMBL3141732 | 0.74 | MAPK10 (0.39) | — | |
| SCHEMBL9404134 | 0.74 | MAPT (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331558-B1 | PROTECTED MONOMERS AND METHODS OF DEPROTECTION FOR RNA SYNTHESIS | AGILENT TECHNOLOGIES INC (US) | 2018-09-12 | — | — | EP | claimed |
| US-11584773-B2 | Phosphorous protecting groups and methods of preparation and use thereof | AGILENT TECHNOLOGIES, INC. (US) | 2023-02-21 | — | — | US | disclosed |
| EP-3943500-A1 | PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF | Agilent Technologies, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |
| US-20220002334-A1 | PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF | UNIVERSITY OF COLORADO BOULDER | 2022-01-06 | — | — | US | disclosed |
| EP-3137478-B1 | PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF | AGILENT TECHNOLOGIES INC (US) | 2021-09-22 | — | — | EP | disclosed |
| CN-106255697-B | Phosphorus protecting group and preparation method and application thereof | 安捷伦科技有限公司 | 2020-04-28 | — | — | CN | disclosed |
| US-20190194242-A1 | PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF | UNIVERSITY OF COLORADO BOULDER | 2019-06-27 | — | — | US | disclosed |
| US-10196418-B2 | Phosphorous protecting groups and methods of preparation and use thereof | AGILENT TECHNOLOGIES, INC. (US) | 2019-02-05 | — | — | US | disclosed |
| EP-3137478-A2 | PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF | Agilent Technologies, Inc. (US) | 2017-03-08 | — | — | EP | disclosed |
| EP-2540734-B1 | Process and reagents for oligonucleotide synthesis and purification | ALNYLAM PHARMACEUTICALS INC (US) | 2016-03-30 | — | — | EP | disclosed |
| US-8063198-B2 | Processes and reagents for desilylation of oligonucleotides | ALNYLAM PHARMACEUTICALS, INC. (US) | 2011-11-22 | — | — | US | disclosed |
| US-8058448-B2 | Processes and reagents for sulfurization of oligonucleotides | ALNYLAM PHARMACEUTICALS, INC. (US) | 2011-11-15 | — | — | US | disclosed |
| US-20100010069-A1 | Extended Length Borane Phosphonate Nucleic Acid Compounds | The Regents of the University of Colorodo (US) | 2010-01-14 | — | — | US | disclosed |
| US-20090187027-A1 | PROCESSES AND REAGENTS FOR SULFURIZATION OF OLIGONUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2009-07-23 | — | — | US | disclosed |
| US-20090187027-A1 | PROCESSES AND REAGENTS FOR SULFURIZATION OF OLIGONUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2009-07-23 | — | — | US | disclosed |
| US-20090005549-A1 | Processes and Reagents for Desilylation of Oligonucleotides | ALNYLAM PHARMACEUTICALS, INC. (US) | 2009-01-01 | — | — | US | disclosed |
| WO-2007106413-A2 | EXTENDED LENGTH BORANE PHOSPHONATE NUCLEIC ACID COMPOUNDS | REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2007-09-20 | — | — | WO | disclosed |
| US-6380214-B1 | THIOPHENE-3-CARBOXYLIC ACID AMIDE DERIVATIVES | PFIZER INC. | 2002-04-30 | — | — | US | disclosed |
| EP-1187826-A1 | HETEROCYCLIC DERIVATIVES USEFUL AS ANTICANCER AGENTS | Pfizer Products Inc. (US) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000071532-A1 | HETEROCYCLIC DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER PRODUCTS INC. (US) | 2000-11-30 | — | — | WO | disclosed |