Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 10/20 | 0.71 |
| ▸ | CTSG | P08311 | 7/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | RECQL | P46063 | 2/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.67 |
| ▸ | MAOA | P21397 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.65 |
| ▸ | MAOB | P27338 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31238107 | 1.00 | ELANE (0.71) | ELANECTSGALDH1A1MAPTTSHR | |
| SCHEMBL17867433 | 0.84 | ELANE (0.62) | ELANECTSGALDH1A1MAPTTSHR | |
| Obtusifolin SCHEMBL3171011 | 0.84 | EPHX2 (0.67) | ELANECTSGALDH1A1MAPTTSHR | |
| SCHEMBL16432557 | 0.84 | ELANE (0.62) | ELANECTSGALDH1A1MAPTTSHR | |
| SCHEMBL16431803 | 0.84 | ELANE (0.62) | ELANECTSGALDH1A1MAPTTSHR | |
| SCHEMBL3186063 | 0.84 | ELANE (0.62) | ELANECTSGALDH1A1MAPTTSHR | |
| SCHEMBL19461991 | 0.83 | ELANE (1.00) | ELANECTSGALDH1A1MAPTTSHR | |
| SCHEMBL3182091 | 0.83 | BCL2 (0.68) | ELANEALDH1A1MAPTTDP1MEN1 | |
| SCHEMBL30260040 | 0.83 | BCL2 (0.68) | ELANEALDH1A1MAPTTDP1MEN1 | |
| SCHEMBL10949445 | 0.82 | ALDH1A1 (0.67) | ELANECTSGALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132403-B2 | Antihelminthic anthraquinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2006-11-07 | — | — | US | claimed |
| US-6903076-B2 | Antihelminthic anthraquinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2005-06-07 | — | — | US | claimed |
| US-6875746-B1 | Anticancer anthraquinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2005-04-05 | — | — | US | claimed |
| US-6838443-B2 | Antihelminthic anthraquinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2005-01-04 | — | — | US | claimed |
| US-6800615-B2 | PARASITICIDES, NEMATOCIDES | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2004-10-05 | — | — | US | claimed |
| US-20040152645-A1 | Antihelminthic anthraquinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2004-08-05 | — | — | US | claimed |
| US-20040116361-A1 | Antihelminthic anthraquinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2004-06-17 | — | — | US | claimed |
| US-20040106686-A1 | Antihelminthic anthraquinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2004-06-03 | — | — | US | claimed |
| US-20030229032-A1 | Antihelminthic anthraquinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2003-12-11 | — | — | US | claimed |
| WO-2003089577-A2 | ANTIHELMINTHIC ANTHRAQUINONES AND METHOD OF USE THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2003-10-30 | — | — | WO | claimed |
| WO-2003089576-A2 | ANTICANCER ANTHRAQUINONES AND METHOD OF USE THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2003-10-30 | — | — | WO | claimed |
| US-7658937-B2 | Anthraquinones and process for the preparation and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2010-02-09 | — | — | US | disclosed |
| US-7658937-B2 | Anthraquinones and process for the preparation and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2010-02-09 | — | — | US | disclosed |
| US-7651829-B2 | Positive resist material and pattern formation method using the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-01-26 | — | — | US | disclosed |
| EP-1745000-A2 | NOVEL ANTHRAQUINONES AND PROCESS FOR THE PREPARATION AND METHOD OF USE THEREOF | Michigan State University (US) | 2007-01-24 | — | — | EP | disclosed |
| WO-2003089576-A3 | ANTICANCER ANTHRAQUINONES AND METHOD OF USE THEREOF | UNIV MICHIGAN STATE (US) | 2003-12-31 | — | — | WO | disclosed |
| US-20030229032-A1 | Antihelminthic anthraquinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2003-12-11 | — | — | US | disclosed |
| WO-2003089577-A2 | ANTIHELMINTHIC ANTHRAQUINONES AND METHOD OF USE THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2003-10-30 | — | — | WO | disclosed |
| WO-2003089576-A2 | ANTICANCER ANTHRAQUINONES AND METHOD OF USE THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2003-10-30 | — | — | WO | disclosed |
| WO-2003089576-A2 | ANTICANCER ANTHRAQUINONES AND METHOD OF USE THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2003-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030229032-A1 | Antihelminthic anthraquinones and method of use thereof | HRH2, HRH3, HRH1 | ELANE 2841/4885CTSG 1797/4885ALDH1A1 102/4885 |
| US-20040152645-A1 | Antihelminthic anthraquinones and method of use thereof | HRH2, HRH3, HRH1 | ELANE 2841/4885CTSG 1797/4885ALDH1A1 102/4885 |
| US-20040106686-A1 | Antihelminthic anthraquinones and method of use thereof | HRH2, HRH3, HRH1 | ELANE 2841/4885CTSG 1797/4885ALDH1A1 102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.