Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | XBP1 | P17861 | 1/20 | 0.62 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.62 |
| ▸ | MITF | O75030 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11371962 | 0.83 | FEN1 (0.50) | MAPTALDH1A1NPSR1LMNANPC1 | |
| SCHEMBL3195204 | 0.83 | FEN1 (0.47) | MAPTALDH1A1NPSR1LMNANPC1 | |
| SCHEMBL30541541 | 0.83 | FEN1 (0.50) | MAPTALDH1A1NPSR1LMNANPC1 | |
| SCHEMBL11365339 | 0.82 | FEN1 (0.49) | MAPTALDH1A1NPSR1LMNANPC1 | |
| SCHEMBL11365344 | 0.82 | FEN1 (0.49) | MAPTALDH1A1NPSR1LMNANPC1 | |
| SCHEMBL11365341 | 0.82 | FEN1 (0.49) | MAPTALDH1A1NPSR1LMNANPC1 | |
| SCHEMBL7270373 | 0.81 | PDE4A (0.54) | MAPTALDH1A1NPSR1LMNANPC1 | |
| SCHEMBL7271280 | 0.80 | FEN1 (0.50) | MAPTALDH1A1NPSR1LMNANPC1 | |
| SCHEMBL4851951 | 0.78 | HSPD1 (0.67) | MAPTALDH1A1NPSR1LMNANPC1 | |
| SCHEMBL29516939 | 0.77 | MAPT (1.00) | MAPTALDH1A1NPSR1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678909-B1 | 2-[2-(3-Amino-cyclohexyl)-5-benzyl-4-oxo-4,5-dihydro-imidazo[4,5-c]pyridin-3-ylmethyl]-benzonitrile; type 2 diabetes mellitus, diabetic dislipidemia, impaired glucose tolerance; female infertility, osteoporosis, male contraception and neurological disorders | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-03-16 | — | — | US | disclosed |
| US-7169926-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-30 | — | — | US | disclosed |