Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.37 |
| ▸ | FDPS | P14324 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL486866 | 0.97 | TSHR (0.43) | TSHROPRM1LMNADNM1THRB | |
| SCHEMBL28129612 | 0.97 | TSHR (0.43) | TSHROPRM1LMNADNM1THRB | |
| SCHEMBL28129611 | 0.97 | TSHR (0.43) | TSHROPRM1LMNADNM1THRB | |
| SCHEMBL3979603 | 0.97 | TSHR (0.43) | TSHROPRM1LMNADNM1THRB | |
| SCHEMBL8044861 | 0.97 | TSHR (0.43) | TSHROPRM1LMNADNM1THRB | |
| SCHEMBL3978555 | 0.97 | TSHR (0.43) | TSHROPRM1LMNADNM1THRB | |
| SCHEMBL3142817 | 0.97 | TSHR (0.43) | TSHROPRM1LMNADNM1THRB | |
| SCHEMBL27634401 | 0.97 | TSHR (0.43) | TSHROPRM1LMNADNM1THRB | |
| SCHEMBL325130 | 0.92 | — | — | |
| Bicarbonate SCHEMBL11767455 | 0.87 | GPR84 (0.52) | TSHRGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970166-A1 | METHOD OF MANUFACTURE OF OCTANEDIOIC ACID, PRECURSORS, AND DERIVATIVES | Segetis, Inc. (US) | 2016-01-20 | — | — | EP | claimed |
| CN-105189470-A | Method of manufacture of octanedioic acid, precursors, and derivatives | SEGETIS INC | 2015-12-23 | — | — | CN | claimed |
| WO-2014150384-A1 | METHOD OF MANUFACTURE OF OCTANEDIOIC ACID, PRECURSORS, AND DERIVATIVES | SEGETIS, INC. (US) | 2014-09-25 | — | — | WO | claimed |
| CN-102522590-A | Non-aqueous organic electrolyte, lithium ion secondary battery containing non-aqueous organic electrolyte, preparation method of lithium ion secondary battery and terminal communication equipment | HUAWEI TECH CO LTD | 2012-06-27 | — | — | CN | claimed |
| JP-9124980-A | — | — | None | — | — | JP | disclosed |
| US-20250309494-A1 | BATTERY | ZHUHAI COSMX BATTERY CO., LTD. (CN) | 2025-10-02 | — | — | US | disclosed |
| US-12209184-B2 | Asphalt additives | ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) | 2025-01-28 | — | — | US | disclosed |
| CN-116194547-B | Nitrile solvent | 奥升德功能材料运营有限公司 | 2024-12-27 | — | — | CN | disclosed |
| US-12006493-B2 | Nitrile solvents | ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) | 2024-06-11 | — | — | US | disclosed |
| EP-4342009-A1 | HIGH VOLUME MANUFACTURING OF ALLOY ANODES FOR LI-ION BATTERY | Applied Materials, Inc. (US) | 2024-03-27 | — | — | EP | disclosed |
| CN-114585673-B | Asphalt additive | 奥升德功能材料运营有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-111936461-B | Process for producing dicyanoalkane and bis (aminomethyl) alkane | 三菱瓦斯化学株式会社 | 2023-09-05 | — | — | CN | disclosed |
| EP-1344774-A1 | Synthesizing methods of dicyanomethylidene compound and heterocyclic compound | FUJI PHOTO FILM CO., LTD. (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-20020058699-A1 | Methods for treating seizure disorders by inhibiting MAPK pathway activation | BAYLOR COLLEGE OF MEDICINE | 2002-05-16 | — | — | US | disclosed |
| WO-2002002097-A2 | METHODS FOR TREATING SEIZURE DISORDERS BY INHIBITING MAPK PATHWAY ACTIVATION WITH NITRILES | SWEATT J DAVID (US) | 2002-01-10 | — | — | WO | disclosed |
| EP-1163215-A1 | AMINO-THIO-ACRYLONITRILES AS MEK INHIBITORS | Du Pont Pharmaceuticals Company (US) | 2001-12-19 | — | — | EP | disclosed |
| CN-1303396-A | Polymerization method | KANEGAFUCHI CHEMICAL IND (JP) | 2001-07-11 | — | — | CN | disclosed |
| US-6153784-A | REMOVING THE HALIDE-CONTAINING PHASE-TRANSFER CATALYST, USED TO PREPARE NITRILES BY REACTING HALOALKANES AND METAL CYANIDES, BY HEATING; ADDING A BASE OF GROUP 1A METAL HYDROXIDES, CARBONATES OR BICARBONATES AND SEPARATING | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-28 | — | — | US | disclosed |
| WO-2000056706-A1 | AMINO-THIO-ACRYLONITRILES AS MEK INHIBITORS | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-09-28 | — | — | WO | disclosed |
| JP-H09124980-A | WATER-BASED RECORDING LIQUID FOR INK JET RECORDING | FUJI PHOTO FILM CO LTD | 1997-05-13 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058699-A1 | Methods for treating seizure disorders by inhibiting MAPK pathway activation | MAPKAPK2, MAPK1, MAPK4 | TSHR 3602/4885OPRM1 2489/4885LMNA 3412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.