⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1177955 | 0.69 | — | — | |
| SCHEMBL2241254 | 0.65 | NOTUM (0.41) | — | |
| SCHEMBL5005927 | 0.64 | — | — | |
| SCHEMBL13517275 | 0.61 | — | — | |
| SCHEMBL9468539 | 0.59 | — | — | |
| SCHEMBL28497580 | 0.58 | — | — | |
| SCHEMBL8776850 | 0.57 | — | — | |
| SCHEMBL1520375 | 0.57 | RAB9A (0.43) | — | |
| SCHEMBL31058753 | 0.56 | — | — | |
| SCHEMBL31058751 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678790-B2 | Platelet ADP receptor inhibitors | PORTOLA PHARMACEUTICALS, INC. (US) | 2010-03-16 | — | — | US | claimed |
| CN-117357538-A | Tripterine and derivatives for the treatment of obesity | 儿童医学中心公司 | 2024-01-09 | — | — | CN | disclosed |
| WO-2023165551-A1 | SIX-MEMBERED AROMATIC RING-PYRROLIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 上海海雁医药科技有限公司 | 2023-09-07 | — | — | WO | disclosed |
| CN-116601131-A | CTPS1 inhibitor and application thereof | 林伯士克洛索有限公司 | 2023-08-15 | — | — | CN | disclosed |
| US-11207420-B2 | Cytotoxin and conjugate, uses of same and preparation method therefor | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2021-12-28 | — | — | US | disclosed |
| US-20210115055-A1 | LRRK2 INHIBITORS AND METHODS OF MAKING AND USING THE SAME | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-04-22 | — | — | US | disclosed |
| US-20200179529-A1 | CYTOTOXIN AND CONJUGATE, USES OF SAME AND PREPARATION METHOD THEREFOR | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2020-06-11 | — | — | US | disclosed |
| EP-3617221-A1 | CYTOTOXIN AND CONJUGATE, USES OF SAME, AND PREPARATION METHOD THEREFOR | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2020-03-04 | — | — | EP | disclosed |
| WO-2019154120-A1 | CYTOTOXIC AGENT AND CONJUGATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-08-15 | — | — | WO | disclosed |
| WO-2019149116-A1 | METHOD FOR PREPARING CONJUGATE | 四川科伦博泰生物医药股份有限公司 | 2019-08-08 | — | — | WO | disclosed |
| US-9220928-B2 | Plant extracts from Acronychia species and their use | ECOBIOTICS LTD (AU) | 2015-12-29 | — | — | US | disclosed |
| US-8404690-B2 | Piperazine-2-carboxamide derivatives | MERCK SERONO SA (CH) | 2013-03-26 | — | — | US | disclosed |
| US-20110318439-A1 | PLANT EXTRACTS FROM ACRONYCHIA SPECIES AND THEIR USE | ECOBIOTICS LTD (AU) | 2011-12-29 | — | — | US | disclosed |
| US-7678790-B2 | Platelet ADP receptor inhibitors | PORTOLA PHARMACEUTICALS, INC. (US) | 2010-03-16 | — | — | US | disclosed |
| US-20070155719-A1 | Platelet ADP receptor inhibitors | PORTOLA PHARMACEUTICALS, INC. (US) | 2007-07-05 | — | — | US | disclosed |
| EP-1296699-A4 | THERAPEUTIC AGENTS - III | PEPLIN RESEARCH PTY LTD (AU) | 2005-02-16 | — | — | EP | disclosed |
| EP-1296699-A1 | THERAPEUTIC AGENTS - III | Peplin Research Pty Ltd (AU) | 2003-04-02 | — | — | EP | disclosed |
| WO-2001093883-A1 | THERAPEUTIC AGENTS - III | PEPLIN RESEARCH PTY LTD (AU) | 2001-12-13 | — | — | WO | disclosed |
| US-4900728-A | ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1990-02-13 | — | — | US | disclosed |