Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12635836 | 0.83 | HPGD (0.63) | HPGDLMNAKMT2AALDH1A1GAA | |
| SCHEMBL9903804 | 0.82 | LMNA (0.52) | LMNAMEN1KMT2AATMALDH1A1 | |
| SCHEMBL1361424 | 0.79 | HPGD (0.54) | HPGDLMNAALDH1A1GAAHTT | |
| SCHEMBL30362267 | 0.79 | HPGD (0.54) | HPGDLMNAALDH1A1GAAHTT | |
| SCHEMBL6927546 | 0.79 | GAA (0.65) | HPGDLMNAALDH1A1GAAHTT | |
| SCHEMBL14415935 | 0.79 | HPGD (0.57) | HPGDLMNAKMT2AALDH1A1GAA | |
| SCHEMBL31371288 | 0.77 | HPGD (0.56) | HPGDLMNAALDH1A1GAAHTT | |
| SCHEMBL4155356 | 0.77 | HPGD (0.56) | HPGDLMNAALDH1A1GAAHTT | |
| SCHEMBL13141012 | 0.77 | HPGD (0.52) | HPGDLMNAALDH1A1GAAHTT | |
| SCHEMBL3010907 | 0.77 | KDM4E (0.60) | HPGDLMNAMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012026495-A1 | NOVEL HYDANTOIN DERIVATIVE AND MEDICINAL AGENT COMPRISING SAME AS ACTIVE INGREDIENT | 杏林製薬株式会社 (JP) | 2012-03-01 | — | — | WO | disclosed |