Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.60 |
| ▸ | GMNN | O75496 | 3/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22392373 | 0.89 | CYP1A2 (0.62) | LMNASMN1; SMN2CYP1A2MAPTMEN1 | |
| SCHEMBL20742884 | 0.88 | LMNA (0.62) | LMNASMN1; SMN2CYP1A2MAPTMEN1 | |
| SCHEMBL19923321 | 0.88 | LMNA (0.62) | LMNASMN1; SMN2CYP1A2MAPTMEN1 | |
| SCHEMBL19923320 | 0.88 | LMNA (0.62) | LMNASMN1; SMN2CYP1A2MAPTMEN1 | |
| SCHEMBL28916570 | 0.88 | LMNA (0.62) | LMNASMN1; SMN2CYP1A2MAPTMEN1 | |
| SCHEMBL12137165 | 0.86 | LMNA (0.64) | LMNASMN1; SMN2CYP1A2MAPTMEN1 | |
| SCHEMBL25186738 | 0.85 | CYP1A2 (0.70) | LMNASMN1; SMN2CYP1A2MAPTMEN1 | |
| SCHEMBL22717093 | 0.85 | LMNA (0.51) | LMNASMN1; SMN2CYP1A2MAPTMEN1 | |
| SCHEMBL28581905 | 0.85 | LMNA (0.58) | LMNASMN1; SMN2CYP1A2MAPTMEN1 | |
| SCHEMBL27906323 | 0.85 | LMNA (0.58) | LMNASMN1; SMN2CYP1A2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655259-B2 | Delayed release carnitine | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A (IT) | 2010-02-02 | — | — | US | disclosed |
| US-20070160669-A1 | DELAYED RELEASE CARNITINE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-07-12 | — | — | US | disclosed |
| US-20060013887-A1 | Delayed release carnitine | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2006-01-19 | — | — | US | disclosed |
| US-20030170290-A1 | Delayed release carnitine | SHUG AUSTIN L (US) | 2003-09-11 | — | — | US | disclosed |