SCHEMBL3194036

SCHEMBL3194036

CCCc1cc(CCC)c([S+](c2ccccc2)c2ccccc2)c(CCC)c1.O=S(=O)([O-])c1c(C(F)(F)F)cc(C(F)(F)F)cc1C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLQ O75417 3/20 0.32
TRPV1 Q8NER1 1/20 0.31
PTGDR2 Q9Y5Y4 2/20 0.31
TRPM8 Q7Z2W7 1/20 0.31
HSD11B1 P28845 1/20 0.30
KIFC1 Q9BW19 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3197511 0.89 POLQ (0.34) POLQTRPV1PTGDR2TRPM8HSD11B1
SCHEMBL3197933 0.88 POLQ (0.34) POLQPTGDR2TRPM8
SCHEMBL3189842 0.87 PTGDR2 (0.37) TRPV1PTGDR2TRPM8HSD11B1
SCHEMBL3183460 0.86
SCHEMBL3204378 0.82 KAT6A (0.33)
SCHEMBL3182835 0.81 KAT6A (0.34)
SCHEMBL3201678 0.80 CYP1A2 (0.41) POLQPTGDR2
SCHEMBL3197571 0.79 KMT2A (0.36)
SCHEMBL3194657 0.79 CYP1A2 (0.36) POLQ
SCHEMBL3197629 0.77 POLQ (0.35) POLQPTGDR2TRPM8HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US disclosed