Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC1 | P19801 | 2/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL318775 | 0.78 | AOC1 (0.38) | AOC1AOC3KDM4EMEN1KDM6B | |
| SCHEMBL1911019 | 0.77 | AOC3 (0.33) | AOC1AOC3KDM4EMEN1KDM6B | |
| SCHEMBL19849321 | 0.77 | AOC3 (0.33) | AOC1AOC3KDM4EMEN1KDM6B | |
| SCHEMBL319870 | 0.77 | AOC3 (0.33) | AOC1AOC3KDM4EMEN1KDM6B | |
| SCHEMBL4846202 | 0.76 | MAPKAPK2 (0.35) | MAPKAPK2 | |
| SCHEMBL15779443 | 0.75 | ATR (0.43) | AOC1AOC3KDM4EMEN1KDM6B | |
| SCHEMBL28231843 | 0.75 | — | — | |
| SCHEMBL14902619 | 0.74 | AOC1 (0.31) | AOC1AOC3 | |
| SCHEMBL14902618 | 0.74 | AOC1 (0.31) | AOC1AOC3 | |
| SCHEMBL29939336 | 0.71 | RPS6KA3 (0.50) | AOC1AOC3KDM4EMEN1KDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590968-A1 | CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS | Novartis AG (CH) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004217-A1 | CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2012-01-12 | — | — | WO | disclosed |