SCHEMBL3194355

SCHEMBL3194355

Nc1cc(S(=O)(=O)O)c2cccc(S(=O)(=O)O)c2c1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AURKA O14965 1/20 0.57
AURKB Q96GD4 1/20 0.57
TTR P02766 1/20 0.56
CYP1A2 P05177 2/20 0.44
NR4A1 P22736 1/20 0.43
ATIC P31939 2/20 0.43
NQO1 P15559 1/20 0.42
SNCA P37840 3/20 0.41
MEN1 O00255 2/20 0.41
ALDH1A1 P00352 2/20 0.41
APP P05067 2/20 0.41
MAPT P10636 2/20 0.41
THRB P10828 2/20 0.41
HPGD P15428 2/20 0.41
RECQL P46063 2/20 0.41
BLM P54132 2/20 0.41
KMT2A Q03164 2/20 0.41
ALOX12 P18054 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
MPL P40238 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7089586 0.86 TTR (0.56) AURKAAURKBTTRCYP1A2NR4A1
SCHEMBL9189207 0.86 AURKA (0.47) AURKAAURKBTTRCYP1A2ATIC
SCHEMBL28865539 0.85 TTR (0.54) AURKAAURKBTTRCYP1A2NR4A1
SCHEMBL13515228 0.84 AURKA (0.50) AURKAAURKBTTRCYP1A2ATIC
SCHEMBL9150920 0.82 AURKA (0.49) AURKAAURKBTTRCYP1A2NR4A1
SCHEMBL9465432 0.81 AURKA (0.55) AURKAAURKBTTRCYP1A2NR4A1
SCHEMBL3203908 0.81 AURKA (0.59) AURKAAURKBTTRCYP1A2NR4A1
SCHEMBL3505111 0.81 TTR (0.53) AURKAAURKBTTRCYP1A2ATIC
SCHEMBL8421029 0.80 TTR (0.56) AURKAAURKBTTRCYP1A2NQO1
Hydrochloric Acid SCHEMBL5733553 0.79 AURKB (0.65) AURKAAURKBTTRCYP1A2NR4A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333472-A1 Binding Domain Mapping and Compounds, Compositions, Complexes, Methods, and Kits Related Thereto GEORGE MASON RES FOUNDATION INC (US) 2025-10-30 US disclosed
US-12331096-B2 Binding domain mapping and compounds, compositions, complexes, methods, and kits related thereto George Mason Research Foundation, Inc. (US) 2025-06-17 US disclosed
EP-2123724-B1 AQUEOUS INK COMPOSITION FOR BALLPOINT PEN PILOT INK CO LTD (JP) 2018-05-23 EP disclosed
US-8764333-B2 Water based ink compositions for ballpoint pen THE PILOT INK CO., LTD. (JP) 2014-07-01 US disclosed
US-20100040401-A1 Water Based Ink Compositions For Ballpoint Pen THE PILOT INK CO., LTD. (JP) 2010-02-18 US disclosed
EP-2123724-A1 AQUEOUS INK COMPOSITION FOR BALLPOINT PEN THE PILOT INK CO., LTD. (JP) 2009-11-25 EP disclosed
EP-0998531-B1 REACTIVE DYES CONTAINING PIPERAZINE DYSTAR TEXTILFARBEN GMBH & CO (DE) 2002-03-06 EP disclosed
US-6248871-B1 DYES CAN BE APPLIED AT A PH ABOVE 7 BY, FOR EXAMPLE, EXHAUST DYEING, PADDING OR PRINTING. BASF AKTIENGESELLSCHAFT (DE) 2001-06-19 US disclosed
EP-0309406-B2 Reactive dyes, their preparation and their use CIBA SC HOLDING AG (CH) 2000-07-12 EP disclosed
EP-0838504-B1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DYSTAR TEXTILFARBEN GMBH & CO (DE) 2000-06-07 EP disclosed
US-4163675-A CONTAINING NAPHTHALENE DERIVATIVES PILOT INK CO., LTD. (JP) 1979-08-07 US disclosed
US-4141890-A FIBER-REACTIVE CIBA-GEIGY CORPORATION (US) 1979-02-27 US disclosed
US-RE29585-E DYEING WOOL CIBA-GEIGY CORPORATION (US) 1978-03-21 US disclosed
US-4067864-A FOR CELLULOSE OR POLYAMIDES CIBA-GEIGY AG (CH) 1978-01-10 US disclosed
US-4039523-A YELLOW CIBA-GEIGY AG (CH) 1977-08-02 US disclosed
US-4017477-A 3-Halogeno-6-hydroxy-pyridone-(2) azo dyestuffs CIBA-GEIGY AG (CH) 1977-04-12 US disclosed
US-4001205-A WATER-SOLUBLE, FIBER-REACTIVE PHENYLAZODIHYDROXY, METHYL, CYANOPYRIDINE DYESTUFFS CIBA-GEIGY AG (CH) 1977-01-04 US disclosed
US-3971738-A Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component CIBA-GEIGY AG (CH) 1976-07-27 US disclosed
US-3956263-A 4-Methyl-2,6-dihydroxy-3-cyanopyridine containing dyestuffs CIBA-GEIGY AG (CH) 1976-05-11 US disclosed
US-3933785-A Azo compounds CIBA-GEIGY AG (CH) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333472-A1 Binding Domain Mapping and Compounds, Compositions, Complexes, Methods, and Kits Related Thereto SNRPE, SSBP1, RPA1 AURKA 3644/4885AURKB 1915/4885TTR 1012/4885
US-12331096-B2 Binding domain mapping and compounds, compositions, complexes, methods, and kits related thereto SNRPE, SSBP1, RPA1 AURKA 3644/4885AURKB 1915/4885TTR 1012/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.