Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.53 |
| ▸ | SUMO2 | P61956 | 4/20 | 0.43 |
| ▸ | SUMO1 | P63165 | 4/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.43 |
| ▸ | SENP2 | Q9HC62 | 4/20 | 0.43 |
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.43 |
| ▸ | SNCA | P37840 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3505111 | 0.88 | TTR (0.53) | TTRAURKAAURKBSUMO2SUMO1 | |
| SCHEMBL3194355 | 0.86 | AURKA (0.57) | TTRAURKAAURKBSUMO2SUMO1 | |
| Hydrochloric Acid SCHEMBL5733553 | 0.85 | AURKB (0.65) | TTRAURKAAURKBSUMO2SUMO1 | |
| SCHEMBL9465432 | 0.85 | AURKA (0.55) | TTRAURKAAURKBSUMO2SUMO1 | |
| SCHEMBL28865539 | 0.85 | TTR (0.54) | TTRAURKAAURKBSUMO2SUMO1 | |
| SCHEMBL1891641 | 0.80 | SENP2 (0.58) | TTRAURKAAURKBSUMO2SUMO1 | |
| SCHEMBL31222829 | 0.80 | SENP2 (0.58) | TTRAURKAAURKBSUMO2SUMO1 | |
| SCHEMBL159399 | 0.79 | AURKA (0.75) | TTRAURKAAURKBSUMO2SUMO1 | |
| SCHEMBL30822934 | 0.79 | AURKA (0.75) | TTRAURKAAURKBSUMO2SUMO1 | |
| SCHEMBL4456435 | 0.79 | SENP2 (0.56) | TTRAURKAAURKBSUMO2SUMO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328588-A1 | METAL COMPLEX COLOURING AGENTS BASED ON BUCHERER NAPHTHOLS | DyStar Textilfarben GmbH & Co. Deutschland KG (DE) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002033006-A1 | METAL COMPLEX COLOURING AGENTS BASED ON BUCHERER NAPHTHOLS | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2002-04-25 | — | — | WO | disclosed |
| EP-0304926-A2 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1989-03-01 | — | — | EP | disclosed |