Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27818487 | 0.92 | NQO2 (0.43) | NQO2CA1CA2L3MBTL1CASP3 | |
| SCHEMBL3192196 | 0.84 | PPARG (0.41) | NQO2L3MBTL1CASP3SENP7SENP6 | |
| SCHEMBL3192190 | 0.84 | PPARG (0.41) | NQO2L3MBTL1CASP3SENP7SENP6 | |
| SCHEMBL27701168 | 0.80 | BCL2 (0.43) | L3MBTL1MEN1KMT2APOLBRAB9A | |
| SCHEMBL2220680 | 0.79 | MAPT (0.53) | NQO2CA1CA2L3MBTL1CASP3 | |
| SCHEMBL2220683 | 0.79 | MAPT (0.53) | NQO2CA1CA2L3MBTL1CASP3 | |
| SCHEMBL3185919 | 0.78 | PPARG (0.45) | L3MBTL1MEN1KMT2APOLBRAB9A | |
| SCHEMBL3185911 | 0.78 | PPARG (0.45) | L3MBTL1MEN1KMT2APOLBRAB9A | |
| SCHEMBL8026026 | 0.78 | TDP1 (0.60) | L3MBTL1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL3188163 | 0.76 | PPARG (0.39) | NQO2MEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867683-B1 | NOVEL POLYMERIZABLE DYE AND OPHTHALMIC LENS CONTAINING THE SAME | MENICON CO LTD (JP) | 2012-10-17 | — | — | EP | disclosed |
| US-7662937-B2 | Polymerizable dye and ophthalmic lens containing the same | MENICON CO., LTD. (JP) | 2010-02-16 | — | — | US | disclosed |
| US-20090082553-A1 | Novel Polymerizable Dye and Ophthalmic Lens Containing the Same | MENICON CO., LTD. (JP) | 2009-03-26 | — | — | US | disclosed |
| EP-1867683-A1 | NOVEL POLYMERIZABLE DYE AND OPHTHALMIC LENS CONTAINING THE SAME | MENICON CO., LTD. (JP) | 2007-12-19 | — | — | EP | disclosed |