Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2220680 | 1.00 | MAPT (0.53) | MAPTKDM4EALDH1A1ALOX5GAA | |
| SCHEMBL2221650 | 0.87 | FTO (0.62) | MAPTKDM4EALDH1A1ALOX5GAA | |
| SCHEMBL2221644 | 0.87 | FTO (0.62) | MAPTKDM4EALDH1A1ALOX5GAA | |
| SCHEMBL20574225 | 0.81 | CA2 (0.56) | MAPTKDM4EALDH1A1ALOX5GAA | |
| SCHEMBL20574224 | 0.81 | CA2 (0.56) | MAPTKDM4EALDH1A1ALOX5GAA | |
| SCHEMBL3194533 | 0.79 | NQO2 (0.46) | MAPTKDM4EALDH1A1GAACA2 | |
| SCHEMBL21650599 | 0.78 | KMT2A (0.53) | MAPTKDM4EALDH1A1ALOX5GAA | |
| SCHEMBL12374390 | 0.74 | MEN1 (0.70) | MAPTALDH1A1CA2MAPK1EGFR | |
| SCHEMBL3870420 | 0.74 | TDP1 (0.62) | MAPTKDM4EALDH1A1CA2L3MBTL1 | |
| SCHEMBL21786993 | 0.73 | CA1 (0.46) | MAPTKDM4EALDH1A1GAABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2526153-B1 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | NOVARTIS AG (CH) | 2014-04-30 | — | — | EP | disclosed |
| CN-102712815-B | Visible light absorbers for ophthalmic lens materials | NOVARTIS AG | 2013-12-25 | — | — | CN | disclosed |
| US-8329775-B2 | Visible light absorbers for ophthalmic lens materials | NOVARTIS AG (CH) | 2012-12-11 | — | — | US | disclosed |
| CN-102712815-A | Visible light absorbers for ophthalmic lens materials | NOVARTIS AG | 2012-10-03 | — | — | CN | disclosed |
| US-20110178202-A1 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | ALCON, INC. (CH) | 2011-07-21 | — | — | US | disclosed |
| WO-2011088449-A1 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | ALCON, INC. (CH) | 2011-07-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178202-A1 | VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS | CRY1, CRY2, CRYAA | MAPT 557/4885KDM4E 1154/4885ALDH1A1 624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.