Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | SLC29A1 | Q99808 | 5/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.46 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3196772 | 0.84 | HSD17B10 (0.62) | HSD17B10KCNH2CYP2D6HTR1A | |
| Hydrochloric Acid SCHEMBL3188909 | 0.83 | HSD17B10 (0.60) | HSD17B10KCNH2CYP2D6HTR2AHTR1A | |
| SCHEMBL3196645 | 0.82 | HSD17B10 (0.71) | HSD17B10KCNH2CYP2D6HTR2AHTR1A | |
| SCHEMBL3197277 | 0.82 | SLC29A1 (0.54) | SLC29A1KCNH2CYP2D6LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3194761 | 0.81 | HSD17B10 (0.69) | HSD17B10KCNH2CYP2D6HTR2AHTR1A | |
| SCHEMBL3186225 | 0.77 | HSD17B10 (0.91) | HSD17B10KCNH2CYP2D6MEN1KMT2A | |
| SCHEMBL3198597 | 0.76 | KCNH2 (0.84) | HSD17B10KCNH2CYP2D6HTR2AHTR2B | |
| SCHEMBL30873546 | 0.76 | KCNH2 (0.84) | HSD17B10KCNH2CYP2D6HTR2AHTR2B | |
| SCHEMBL11179651 | 0.76 | USP2 (0.69) | HSD17B10LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11347208 | 0.75 | HSD17B10 (0.89) | HSD17B10KCNH2CYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029682-A1 | NOVEL CHROMENE AND THIOCHROMENE CARBOXAMIDE DERIVATIVES, METHODS FOR PREPARING SAME AND THERAPEUTIC APPLICATIONS OF SAME | PIERRE FABRE MEDICAMENT (FR) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029682-A1 | NOVEL CHROMENE AND THIOCHROMENE CARBOXAMIDE DERIVATIVES, METHODS FOR PREPARING SAME AND THERAPEUTIC APPLICATIONS OF SAME | DRD3, CHRNA3, CHRM3 | HSD17B10 1343/4885SLC29A1 4087/4885KCNH2 1015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.