SCHEMBL319782

SCHEMBL319782

B.c1ccc(C2CNCCO2)cc1

nearest known ligand 0.63

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.63
DRD3 P35462 1/20 0.63
HTR1A P08908 1/20 0.58
HTR2A P28223 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4536932 0.98 DRD2 (0.65) DRD2DRD3HTR1AHTR2A
SCHEMBL8538844 0.98 DRD2 (0.65) DRD2DRD3HTR1AHTR2A
SCHEMBL1626963 0.98 DRD2 (0.65) DRD2DRD3HTR1AHTR2A
SCHEMBL357358 0.98 DRD2 (0.65) DRD2DRD3HTR1AHTR2A
Ammonia Solution, Strong SCHEMBL27880976 0.96 DRD2 (0.63) DRD2DRD3HTR1AHTR2A
SCHEMBL28845061 0.96 DRD2 (0.63) DRD2DRD3HTR1AHTR2A
Hydrochloric Acid SCHEMBL1711121 0.96 DRD2 (0.63) DRD2DRD3HTR1AHTR2A
SCHEMBL28148490 0.96 DRD2 (0.63) DRD2DRD3HTR1AHTR2A
SCHEMBL27453341 0.88 DRD2 (0.59) DRD2DRD3
SCHEMBL19866138 0.87 DRD2 (0.53) DRD2DRD3HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8637703-B2 Methods for synthesizing ammonia borane THE OHIO STATE UNIVERSITY (US) 2014-01-28 US claimed
EP-2007743-B1 METHODS FOR SYNTHESIZING AMMONIA BORANE UNIV OHIO STATE (US) 2013-06-12 EP claimed
US-20120014857-A1 METHODS FOR SYNTHESIZING AMMONIA BORANE THE OHIO STATE UNIVERSITY (US) 2012-01-19 US claimed
US-7977508-B2 Methods for synthesizing ammonia borane THE OHIO STATE UNIVERSITY (US) 2011-07-12 US claimed
US-20090104102-A1 METHODS FOR SYNTHESIZING AMMONIA BORANE THE OHIO STATE UNIVERSITY 2009-04-23 US claimed
EP-2007743-A2 METHODS FOR SYNTHESIZING AMMONIA BORANE The Ohio State University (US) 2008-12-31 EP claimed
WO-2007120511-A2 METHODS FOR SYNTHESIZING AMMONIA BORANE THE OHIO STATE UNIVERSITY (US) 2007-10-25 WO claimed
US-20050173254-A1 Nickel cobalt boron ternary alloys TASKEM, INC. 2005-08-11 US claimed
US-4243803-A Production of 7-(2-aminomethylphenylacetamido)-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid BRISTOL-MYERS COMPANY (US) 1981-01-06 US claimed
US-10370254-B2 Method for producing borazane AIRBUS SAFRAN LAUNCHERS SAS (FR) 2019-08-06 US disclosed
EP-3145863-B1 METHOD FOR PRODUCING BORAZANE ARIANEGROUP SAS (FR) 2018-10-17 EP disclosed
US-10002919-B2 High resistivity iron-based, thermally stable magnetic material for on-chip integrated inductors INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-06-19 US disclosed
US-20180012953-A1 HIGH RESISTIVITY IRON-BASED, THERMALLY STABLE MAGNETIC MATERIAL FOR ON-CHIP INTEGRATED INDUCTORS INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-01-11 US disclosed
US-20170305750-A1 METHOD FOR PRODUCING BORAZANE AIRBUS SAFRAN LAUNCHERS SAS (FR) 2017-10-26 US disclosed
EP-2007743-A2 METHODS FOR SYNTHESIZING AMMONIA BORANE The Ohio State University (US) 2008-12-31 EP disclosed
WO-2007120511-A2 METHODS FOR SYNTHESIZING AMMONIA BORANE THE OHIO STATE UNIVERSITY (US) 2007-10-25 WO disclosed
WO-2005078163-A1 TERNARY AND QUATERNARY ALLOYS TO REPLACE CHROMIUM TASKEM, INC. (US) 2005-08-25 WO disclosed
US-20050173255-A1 Electroplated quaternary alloys TASKEM, INC. 2005-08-11 US disclosed
US-20050173254-A1 Nickel cobalt boron ternary alloys TASKEM, INC. 2005-08-11 US disclosed
US-4210590-A WITH BORANE COMPLEX REAGENT IN PRESENCE OF TRIFLUOROACETIC ACID MCNEIL LABORATORIES, INCORPORATED (US) 1980-07-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170305750-A1 METHOD FOR PRODUCING BORAZANE BAD, BAX, BCL2A1 DRD2 1959/4885DRD3 1922/4885HTR1A 1340/4885
US-10370254-B2 Method for producing borazane BAD, BAX, BCL2A1 DRD2 1959/4885DRD3 1922/4885HTR1A 1340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.