SCHEMBL3198

SCHEMBL3198

Oc1cccc2cc3cccc(O)c3c(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
DNMT1 P26358 1/20 1.00
CACNA1B Q00975 1/20 1.00
APBA1 Q02410 1/20 1.00
MCL1 Q07820 1/20 1.00
APOBEC3G Q9HC16 1/20 1.00
HPGD P15428 4/20 0.52
ALOX15 P16050 4/20 0.52
RECQL P46063 4/20 0.52
HSD17B10 Q99714 4/20 0.52
TDP1 Q9NUW8 4/20 0.52
CDK2 P24941 3/20 0.52
MAPT P10636 3/20 0.52
THRB P10828 2/20 0.52
SNCA P37840 2/20 0.52
KDM4E B2RXH2 2/20 0.52
POLB P06746 2/20 0.52
CYP3A4 P08684 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3320154 0.95 ALDH1A1 (0.91) ALDH1A1MEN1KMT2ADNMT1CACNA1B
Acetic Acid SCHEMBL9119537 0.87 KMT2A (0.76) ALDH1A1MEN1KMT2ADNMT1CACNA1B
SCHEMBL10714892 0.87 ALDH1A1 (0.76) ALDH1A1MEN1KMT2ADNMT1CACNA1B
SCHEMBL9742451 0.85 ALDH1A1 (0.73) ALDH1A1MEN1KMT2ADNMT1CACNA1B
SCHEMBL6544581 0.85 ALDH1A1 (0.74) ALDH1A1MEN1KMT2ADNMT1CACNA1B
SCHEMBL5598124 0.84 MEN1 (0.72) ALDH1A1MEN1KMT2ADNMT1CACNA1B
SCHEMBL31035951 0.84 MEN1 (0.72) ALDH1A1MEN1KMT2ADNMT1CACNA1B
SCHEMBL30066036 0.84 MEN1 (0.72) ALDH1A1MEN1KMT2ADNMT1CACNA1B
SCHEMBL29906204 0.84 ALDH1A1 (0.70) ALDH1A1MEN1KMT2ADNMT1CACNA1B
SCHEMBL5858623 0.84 ALDH1A1 (0.70) ALDH1A1MEN1KMT2ADNMT1CACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10302 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260138973-A1 SUBSTITUTED PYRIDINES FOR USE IN TREATING OR PREVENTING INFLAMMATORY DISEASES OR DISEASES ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE SITRYX THERAPEUTICS LTD (GB) 2026-05-21 US claimed
US-20260137680-A1 NOVEL COMPOUNDS SITRYX THERAPEUTICS LTD (GB) 2026-05-21 US claimed
EP-4743098-A1 THERAPEUTIC USE OF FIBROBLASTS FOR THE TREATMENT OF PSORIASIS FibroBiologics, Inc. (US) 2026-05-20 EP claimed
US-12617762-B2 Carboxy derivatives with antiinflamatory properties SITRYX THERAPEUTICS LIMITED (GB) 2026-05-05 US claimed
US-20260085061-A1 PHTHALAZINE DERIVATIVES AS PYRUVATE KINASE MODULATORS SITRYX THERAPEUTICS LIMITED (GB) 2026-03-26 US claimed
EP-4081511-B3 CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES SITRYX THERAPEUTICS LTD (GB) 2026-03-04 EP claimed
EP-4634167-A1 SUBSTITUTED PYRIDINES FOR USE IN TREATING OR PREVENTING INFLAMMATORY DISEASES OR DISEASES ASSOCIATED WITH AN UNDESIRABLE IMMUNE RESPONSE Sitryx Therapeutics Limited (GB) 2025-10-22 EP claimed
US-20250312457-A1 PHARMACEUTICAL COMPOSITIONS OF ROFLUMILAST IN AQUEOUS BLENDS OF WATER-MISCIBLE, PHARMACEUTICALLY ACCEPTABLE SOLVENTS ARCUTIS BIOTHERAPEUTICS INC (US) 2025-10-09 US claimed
EP-3840705-B1 COMPRESSION BANDAGING ANDOVER HEALTHCARE INC (US) 2025-10-01 EP claimed
US-20250295611-A1 METHODS OF TREATING 5HT2A RECEPTOR-MEDIATED CONDITIONS TESSELLATE THERAPEUTICS INC (US) 2025-09-25 US claimed
US-4513011-A Composition in the form of a shampoo based on anthralin L'OREAL (FR) 1985-04-23 US claimed
US-4504494-A Preparation of anthralin solutions or suspensions in aromatic esters and their use for diseases of the skin and nails SOCIETE ANONYME DITE: L'OREAL (FR) 1985-03-12 US claimed
US-4495203-A PSORIASIS SOCIETE ANONYME DITE: L'OREAL (FR) 1985-01-22 US claimed
WO-1985000106-A1 IMPROVED COMPOSITIONS FOR THE TREATMENT OF PSORIASIS STIEFEL LABORATORIES, INC. (US) 1985-01-17 WO claimed
EP-0083359-B1 PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF SKIN Orion-yhtymä Oy (FI) 1985-01-02 EP claimed
EP-0129003-A2 Cosmetic and dermatological compositions containing 1-alpha-hydroxycholecalciferol YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 1984-12-27 EP claimed
EP-0098743-A1 Phenyl alpha-acyloxyacetamide derivates and their therapeutic use Yu, Ruey J., Dr. (US) 1984-01-18 EP claimed
EP-0017420-B1 NEW DIHYDROXY-ACYLANTHRONES HAVING ANTI-PSORIATIC ACTIVITY, PROCESS FOR PREPARING THEM, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM, AND THEIR USE AS ANTI-PSORIATIC AGENTS ORION-YHTYMÄ OY (FI) 1982-07-21 EP claimed
US-4252796-A ALUMINUM COMPOUNDS, ANTIINFLAMMATORY AGENTS YU RUEY J 1981-02-24 US claimed
EP-0017420-A1 New dihydroxy-acylanthrones having anti-psoriatic activity, process for preparing them, pharmaceutical compositions comprising them, and their use as anti-psoriatic agents ORION-YHTYMÄ OY (FI) 1980-10-15 EP claimed