SCHEMBL3198146

SCHEMBL3198146

COC(=O)c1cc(C(=O)OC)c(C(=O)OC)cc1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.47
HSD17B10 Q99714 3/20 0.47
MAPT P10636 2/20 0.47
GAA P10253 2/20 0.47
ALDH1A1 P00352 2/20 0.47
HPGD P15428 2/20 0.47
ATM Q13315 2/20 0.47
GLA P06280 1/20 0.47
CASP1 P29466 1/20 0.47
CASP7 P55210 1/20 0.47
TDP1 Q9NUW8 1/20 0.46
PDGFRB P09619 1/20 0.46
FGFR1 P11362 1/20 0.46
PDGFRA P16234 1/20 0.46
FLT1 P17948 1/20 0.46
FGFR3 P22607 1/20 0.46
KDR P35968 1/20 0.46
CA12 O43570 5/20 0.45
CA1 P00915 5/20 0.45
CA2 P00918 5/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2430255 0.95 KDM4E (0.50) KDM4EHSD17B10MAPTGAAALDH1A1
SCHEMBL3187202 0.93 KDM4E (0.48) KDM4EHSD17B10MAPTGAAALDH1A1
SCHEMBL3207481 0.91 MAPT (0.47) KDM4EHSD17B10MAPTGAAALDH1A1
SCHEMBL232535 0.90 MAPT (0.48) KDM4EHSD17B10MAPTGAAALDH1A1
SCHEMBL829753 0.87 CA12 (0.54) KDM4EHSD17B10MAPTGAAALDH1A1
SCHEMBL30182718 0.86 KDM4E (0.44) KDM4EHSD17B10MAPTGAAALDH1A1
SCHEMBL15957613 0.86 MAPT (0.44) KDM4EHSD17B10MAPTGAAALDH1A1
SCHEMBL4101519 0.86 KDM4E (0.44) KDM4EHSD17B10MAPTGAAALDH1A1
SCHEMBL7323565 0.85 MAPT (0.43) KDM4EHSD17B10MAPTGAAALDH1A1
SCHEMBL15957647 0.85 SMN1; SMN2 (0.43) KDM4EHSD17B10MAPTGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2135671-B1 Catalyst and method for producing carboxylic acid and/or carboxylic anhydride in the presence of the catalyst MITSUBISHI GAS CHEMICAL CO (JP) 2015-03-04 EP disclosed
US-8357625-B2 Catalyst and method for producing carboxylic acid and/or carboxylic anhydride in the presence of the catalyst MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-01-22 US disclosed
US-20100036138-A1 CATALYST AND METHOD FOR PRODUCING CARBOXYLIC ACID AND/OR CARBOXYLIC ANHYDRIDE IN THE PRESENCE OF THE CATALYST MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2010-02-11 US disclosed
EP-2135671-A2 Catalyst and method for producing carboxylic acid and/or carboxylic anhydride in the presence of the catalyst Mitsubishi Gas Chemical Company, Inc. (JP) 2009-12-23 EP disclosed