Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15543935 | 0.94 | PDGFRB (0.42) | MAPTGAAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL2430255 | 0.89 | KDM4E (0.50) | MAPTGAAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL3207481 | 0.85 | MAPT (0.47) | MAPTGAAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL3198146 | 0.85 | KDM4E (0.47) | MAPTGAAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL2154184 | 0.84 | ALDH1A1 (0.37) | MAPTGAAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL3187202 | 0.82 | KDM4E (0.48) | MAPTGAAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL18432300 | 0.82 | GAA (0.46) | MAPTGAAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL4101519 | 0.81 | KDM4E (0.44) | MAPTGAAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL30182718 | 0.81 | KDM4E (0.44) | MAPTGAAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL15957613 | 0.81 | MAPT (0.44) | MAPTGAAKDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |
| EP-1053247-A1 | ANTIFUNGAL CYCLOHEXAPEPTIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999040108-A1 | NEW COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-12 | — | — | WO | disclosed |