Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6387314 | 0.88 | EPHX1 (0.61) | EPHX1ALDH1A1HPGDCYP19A1TSHR | |
| SCHEMBL16194851 | 0.88 | EPHX1 (0.61) | EPHX1ALDH1A1HPGDCYP19A1TSHR | |
| SCHEMBL13932935 | 0.82 | EPHX1 (0.59) | EPHX1ALDH1A1HPGDCYP19A1TSHR | |
| SCHEMBL9715760 | 0.82 | EPHX1 (0.59) | EPHX1ALDH1A1HPGDCYP19A1TSHR | |
| SCHEMBL7927510 | 0.81 | EPHX1 (0.55) | EPHX1ALDH1A1HPGDCYP19A1TSHR | |
| SCHEMBL21831905 | 0.81 | EPHX1 (0.55) | EPHX1ALDH1A1HPGDCYP19A1TSHR | |
| SCHEMBL8592416 | 0.80 | EPHX1 (0.57) | EPHX1ALDH1A1HPGDCYP19A1TSHR | |
| SCHEMBL15305973 | 0.80 | EPHX1 (0.57) | EPHX1ALDH1A1HPGDCYP19A1TSHR | |
| SCHEMBL4637145 | 0.80 | EPHX1 (0.57) | EPHX1ALDH1A1HPGDCYP19A1TSHR | |
| SCHEMBL6696282 | 0.80 | EPHX1 (0.57) | EPHX1ALDH1A1HPGDCYP19A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7666866-B2 | Antithrombotic diamides | ELI LILLY AND COMPANY (US) | 2010-02-23 | — | — | US | claimed |