Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13932935 | 1.00 | EPHX1 (0.59) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL6387314 | 0.93 | EPHX1 (0.61) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL16194851 | 0.93 | EPHX1 (0.61) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL17407566 | 0.87 | EPHX1 (0.62) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL14616021 | 0.87 | EPHX1 (0.62) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL6129364 | 0.87 | EPHX1 (0.62) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL14355425 | 0.87 | EPHX1 (0.62) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL3127776 | 0.87 | EPHX1 (0.62) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL1664553 | 0.86 | EPHX1 (0.66) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL15797823 | 0.86 | EPHX1 (0.66) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114085150-B | Synthesis method of beta- (-) -L-menthyl-acrylic ester compound and application of beta- (-) -L-menthyl-acrylic ester compound in cigarettes | 云南中烟工业有限责任公司 | 2023-10-20 | — | — | CN | claimed |
| EP-0280285-B1 | PROCESS FOR MAKING AND ISOLATING (R)-2-HYDROXY 4-PHENYLBUTYRIC ACID AND ESTERS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-09-02 | — | — | EP | claimed |
| CN-114085150-B | Synthesis method of beta- (-) -L-menthyl-acrylic ester compound and application of beta- (-) -L-menthyl-acrylic ester compound in cigarettes | 云南中烟工业有限责任公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-114085150-B | Synthesis method of beta- (-) -L-menthyl-acrylic ester compound and application of beta- (-) -L-menthyl-acrylic ester compound in cigarettes | 云南中烟工业有限责任公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-114085150-A | Synthetic method of beta- (-) -L-menthyl-acrylate compound and application of beta- (-) -L-menthyl-acrylate compound in cigarettes | 云南中烟工业有限责任公司 | 2022-02-25 | — | — | CN | disclosed |
| US-8344025-B2 | Oxalic acid derivatives and use thereof as physiological cooling active ingredients | SYMRISE AG (DE) | 2013-01-01 | — | — | US | disclosed |
| US-8344025-B2 | Oxalic acid derivatives and use thereof as physiological cooling active ingredients | SYMRISE AG (DE) | 2013-01-01 | — | — | US | disclosed |
| EP-2033688-B1 | Oxalic acid derivatives and their use as physiological cooling agents | SYMRISE AG (DE) | 2012-10-17 | — | — | EP | disclosed |
| EP-2033688-A2 | Oxalic acid derivatives and their use as physiological cooling agents | Symrise GmbH & Co. KG (DE) | 2009-03-11 | — | — | EP | disclosed |
| US-20090054520-A1 | OXALIC ACID DERIVATIVES AND USE THEREOF AS PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS | SYMRISE GMBH & CO. KG (DE) | 2009-02-26 | — | — | US | disclosed |
| US-20090054520-A1 | OXALIC ACID DERIVATIVES AND USE THEREOF AS PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS | SYMRISE GMBH & CO. KG (DE) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054520-A1 | OXALIC ACID DERIVATIVES AND USE THEREOF AS PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS | OTC, OAT, HOGA1 | EPHX1 1362/4885ALDH1A1 763/4885HPGD 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.