SCHEMBL3198627

SCHEMBL3198627

C=C(C)C(=O)OC(C)CC(C)(C)O[SiH3]

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
ALDH1A1 P00352 1/20 0.33
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18121617 0.86 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL8616060 0.86 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL1559806 0.84 TSHR (0.40) TSHRALDH1A1THRB
SCHEMBL6535889 0.83 TSHR (0.37) TSHRALDH1A1THRB
SCHEMBL23494139 0.82 TSHR (0.44) TSHRALDH1A1THRB
SCHEMBL3338092 0.82 TSHR (0.44) TSHR
SCHEMBL6534614 0.81 TSHR (0.38) TSHRALDH1A1
SCHEMBL4654910 0.80 TSHR (0.42) TSHRALDH1A1THRB
SCHEMBL79758 0.80 TSHR (0.33) TSHRALDH1A1THRB
SCHEMBL28795510 0.80 TSHR (0.37) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7638075-B2 Colored printing ink for contact lenses NOVARTIS AG (CH) 2009-12-29 US claimed
EP-1381331-B1 METHOD FOR MAKING A COLORED CONTACT LENS NOVARTIS AG (CH) 2009-03-11 EP claimed
US-6955832-B2 Colored printing ink for contact lenses NOVARTIS AG (CH) 2005-10-18 US claimed
US-20050221105-A1 Colored printing ink for contact lenses ALCON INC. (CH) 2005-10-06 US claimed
EP-1381331-A2 COLORED PRINTING INK FOR CONTACT LENSES Novartis AG (CH) 2004-01-21 EP claimed
US-20030054109-A1 Colored printing ink for contact lenses NOVARTIS AG (CH) 2003-03-20 US claimed
WO-2002074186-A2 COLORED PRINTING INK FOR CONTACT LENSES NOVARTIS AG (CH) 2002-09-26 WO claimed
EP-1756625-B1 CURABLE COLORED INKS FOR MAKING COLORED SILICONE HYDROGEL LENSES NOVARTIS AG (CH) 2014-06-04 EP disclosed
US-20140039086-A1 CURABLE COLORED INKS FOR MAKING COLORED SILICONE NOVARTIS AG (CH) 2014-02-06 US disclosed
US-8622543-B2 Curable colored inks for making colored silicone hydrogel lenses NOVARTIS AG (CH) 2014-01-07 US disclosed
US-7669946-B2 Ink jet printing system for printing colored images on contact lenses NOVARTIS AG (CH) 2010-03-02 US disclosed
US-7638075-B2 Colored printing ink for contact lenses NOVARTIS AG (CH) 2009-12-29 US disclosed
EP-1799436-B1 METHOD FOR MAKING COLORED SILICONE HYDROGEL CONTACT LENSES NOVARTIS AG (CH) 2009-12-02 EP disclosed
WO-2003039878-A1 AN INK JET PRINTING SYSTEM FOR PRINTING COLORED IMAGES ON CONTACT LENSES NOVARTIS AG (CH) 2003-05-15 WO disclosed
US-20030085934-A1 Ink-jet printing system for printing colored images on contact lenses TUCKER ROBERT CAREY 2003-05-08 US disclosed
US-20030054109-A1 Colored printing ink for contact lenses NOVARTIS AG (CH) 2003-03-20 US disclosed
US-20020190407-A1 System and method for treating articles with fluids ALCON INC. (CH) 2002-12-19 US disclosed
EP-1262306-A1 System and method for treating articles like ophthalmic lenses, contact lenses or medical devices with fluids Novartis AG (CH) 2002-12-04 EP disclosed
EP-1216142-A1 THERMOFORMABLE OPHTHALMIC LENS Wesley Jessen Corporation (US) 2002-06-26 EP disclosed
WO-2001005578-A1 THERMOFORMABLE OPHTHALMIC LENS WESLEY-JESSEN CORPORATION (US) 2001-01-25 WO disclosed