SCHEMBL319927

SCHEMBL319927

CCO[Si](CC)(CCCCCCCl)OCC

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
ALDH1A1 P00352 1/20 0.39
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL963461 0.91 TSHR (0.33) TSHRALDH1A1TDP1
SCHEMBL3237907 0.89
SCHEMBL3239121 0.89
SCHEMBL3239917 0.89
SCHEMBL3243281 0.89
SCHEMBL704451 0.86
SCHEMBL29201592 0.83 TSHR (0.39) TSHRALDH1A1TDP1
SCHEMBL5572064 0.82 TSHR (0.38) TSHRALDH1A1
SCHEMBL4735088 0.82 TSHR (0.38) TSHRALDH1A1
SCHEMBL5574671 0.82 TSHR (0.38) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10221200-B2 Quaternary amino alcohol functional organosilicon compounds, composition containing the latter and their production and use EVONIK DEGUSSA GMBH (DE) 2019-03-05 US disclosed
US-9796738-B2 Quaternary amino alcohol functional organosilicon compounds, composition containing the latter and their production and use EVONIK DEGUSSA GMBH (DE) 2017-10-24 US disclosed
US-20170233416-A1 Quaternary amino alcohol functional organosilicon compounds, composition containing the latter and their production and use EVONIK DEGUSSA GMBH (DE) 2017-08-17 US disclosed
EP-2590988-B1 QUATERNARY AMINO ALCOHOL FUNCTIONAL ORGANOSILICON COMPOUNDS, COMPOSITION CONTAINING THE LATTER AND THEIR PRODUCTION AND USE EVONIK DEGUSSA GMBH (DE) 2017-03-01 EP disclosed
CN-102405224-B Comprise composition and the Synthesis and applications thereof of season amino-functional silicoorganic compound EVONIK DEGUSSA GMBH (DE) 2015-12-16 CN disclosed
EP-2421874-B1 COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2015-09-30 EP disclosed
US-8980960-B2 Methods for producing a dispersion containing silicon dioxide particles and cationization agent EVONIK DEGUSSA GMBH (DE) 2015-03-17 US disclosed
US-8979996-B2 Composition containing quaternary amino-functional organosilicon compunds and production and use thereof EVONIK DEGUSSA GMBH (DE) 2015-03-17 US disclosed
US-20140208981-A1 COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2014-07-31 US disclosed
US-8747541-B2 Dispersion containing silica particles surface-modified with quaternary, aminofunctional organosilicon compounds EVONIK DEGUSSA GMBH (DE) 2014-06-10 US disclosed
CN-102405263-A Dispersion containing silicon dioxide particles surface-modified with quaternized amino-functional organosilicon compounds EVONIK DEGUSSA GMBH 2012-04-04 CN disclosed
EP-2421874-A1 COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF Evonik Degussa GmbH (DE) 2012-02-29 EP disclosed
EP-2421921-A1 DISPERSION CONTAINING SILICA PARTICLES SURFACE-MODIFIED WITH QUATERNARY, AMINOFUNCTIONAL ORGANOSILICON COMPOUNDS Evonik Degussa GmbH (DE) 2012-02-29 EP disclosed
US-20120037040-A1 COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2012-02-16 US disclosed
WO-2012004044-A1 METHODS FOR PRODUCING A DISPERSION CONTAINING SILICON DIOXIDE PARTICLES AND CATIONIZATION AGENT EVONIK DEGUSSA GMBH (DE) 2012-01-12 WO disclosed
WO-2012004082-A2 QUATERNARY AMINO ALCOHOL FUNCTIONAL ORGANOSILICON COMPOUNDS, COMPOSITION CONTAINING THE LATTER AND THEIR PRODUCTION AND USE EVONIK DEGUSSA GMBH (DE) 2012-01-12 WO disclosed
US-20120006228-A1 DISPERSION CONTAINING SILICA PARTICLES SURFACE-MODIFIED WITH QUATERNARY, AMINOFUNCTIONAL ORGANOSILICON COMPOUNDS EVONIK DEGUSSA GMBH (DE) 2012-01-12 US disclosed
WO-2010121878-A1 DISPERSION CONTAINING SILICA PARTICLES SURFACE-MODIFIED WITH QUATERNARY, AMINOFUNCTIONAL ORGANOSILICON COMPOUNDS EVONIK DEGUSSA GMBH (DE) 2010-10-28 WO disclosed
WO-2010121873-A1 COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2010-10-28 WO disclosed
US-4390712-A Aqueous solution of cationic organosilicon compounds and process for the production of the solutions DEGUSSA AG (DE) 1983-06-28 US disclosed