SCHEMBL319941

SCHEMBL319941

CCCNC(=O)CC#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11845816 0.98 MCL1 (0.96)
Dimethylamine SCHEMBL5343956 0.96 MCL1 (0.92)
SCHEMBL319448 0.87 MCL1 (0.77)
SCHEMBL6217575 0.85 MCL1 (0.74)
SCHEMBL6317039 0.85 MCL1 (0.74)
SCHEMBL1958608 0.84 MCL1 (0.71)
SCHEMBL1962964 0.84 MCL1 (0.71)
SCHEMBL1962966 0.84 MCL1 (0.71)
SCHEMBL3394896 0.84 MCL1 (0.71)
SCHEMBL1962363 0.84 MCL1 (0.71)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2729510-B1 PROCESS FOR PRODUCING FLEXIBLE POLYURETHANE FOAM USING NATURAL OIL POLYOLS AIR PROD & CHEM (US) 2016-11-16 EP claimed
US-20160002426-A1 Additives for Improving Polyurethane Foam Performance AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-01-07 US claimed
EP-2591031-B1 PROCESS FOR PRODUCING FLEXIBLE POLYURETHANE FOAM AIR PROD & CHEM (US) 2015-06-17 EP claimed
EP-2738192-B1 Process for producing flexible polyurethane foam AIR PROD & CHEM (US) 2015-06-10 EP claimed
EP-2738192-A1 Process for producing flexible polyurethane foam AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-06-04 EP claimed
CN-119638634-A Cinnoline-2-oxide compound, preparation method and application thereof 上海赛默罗生物科技有限公司 2025-03-18 CN disclosed
EP-3494154-B1 POLYURETHANE FOAM FOR THIN WALL APPLICATIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2023-11-22 EP disclosed
CN-109563227-B Polyurethane foams for thin-walled applications 陶氏环球技术有限责任公司 2022-08-26 CN disclosed
WO-2021249475-A1 FUSED QUINAZOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE 江苏恒瑞医药股份有限公司 2021-12-16 WO disclosed
US-10953012-B2 Heterocyclic compounds for the inhibition of pask BIOENERGENIX LLC (US) 2021-03-23 US disclosed
US-10953012-B2 Heterocyclic compounds for the inhibition of pask BIOENERGENIX LLC (US) 2021-03-23 US disclosed
WO-2020240586-A1 NOVEL COMPOUNDS FOR INHIBITION OF JANUS KINASE 1 MANKIND PHARMA LTD. (IN) 2020-12-03 WO disclosed
US-4925844-A ADMINISTERING 4-AMINO-8-PHENYL-N-PROPYL-3-CINNOLINECARBOXAMIDE ICI AMERICAS INC. (US) 1990-05-15 US disclosed
US-4886800-A Substituted cinnoline derivatives as CNS depressants ICI AMERICAS INC. (US) 1989-12-12 US disclosed
EP-0328282-A2 Pharmaceutical ICI AMERICAS INC. (US) 1989-08-16 EP disclosed
EP-0213892-A2 Herbicidally active enols ROHM AND HAAS COMPANY (US) 1987-03-11 EP disclosed
EP-0205272-A2 Cinnoline derivatives ICI AMERICAS INC. (US) 1986-12-17 EP disclosed
US-4098598-A PLANT GROWTH REGULATORS HOFFMANN-LA ROCHE INC. (US) 1978-07-04 US disclosed
US-4028089-A BENZOXAZOLINYLIDENE-MALONITRILE DERIVATIVES HOFFMANN-LA ROCHE INC. (US) 1977-06-07 US disclosed
US-3985763-A DYESTUFFS BAYER AKTIENGESELLSCHAFT (DT) 1976-10-12 US disclosed