Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30610948 | 0.85 | ALDH1A1 (0.58) | MAPK1TSHRALDH1A1NPSR1MAPT | |
| SCHEMBL6816481 | 0.85 | ALDH1A1 (0.58) | MAPK1TSHRALDH1A1NPSR1MAPT | |
| SCHEMBL29686179 | 0.82 | TSHR (0.50) | MAPK1TSHRALDH1A1NPSR1MAPT | |
| SCHEMBL26118896 | 0.82 | TSHR (0.50) | MAPK1TSHRALDH1A1NPSR1MAPT | |
| SCHEMBL3486787 | 0.82 | TSHR (0.50) | MAPK1TSHRALDH1A1NPSR1MAPT | |
| SCHEMBL3486789 | 0.82 | TSHR (0.50) | MAPK1TSHRALDH1A1NPSR1MAPT | |
| SCHEMBL9760432 | 0.80 | TDP1 (0.62) | MAPK1TSHRALDH1A1MAPTLMNA | |
| SCHEMBL29686432 | 0.79 | TSHR (0.47) | MAPK1TSHRALDH1A1NPSR1MAPT | |
| Water SCHEMBL11164211 | 0.79 | TSHR (0.47) | MAPK1TSHRALDH1A1NPSR1MAPT | |
| SCHEMBL26114216 | 0.79 | TSHR (0.47) | MAPK1TSHRALDH1A1NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9468694-B2 | Fluorination process | GE HEALTHCARE LIMITED (GB) | 2016-10-18 | — | — | US | disclosed |
| US-9468694-B2 | Fluorination process | GE HEALTHCARE LIMITED (GB) | 2016-10-18 | — | — | US | disclosed |
| US-20150328344-A1 | Fluorination Process | GE HEALTHCARE AS (NO) | 2015-11-19 | — | — | US | disclosed |
| US-20150328344-A1 | Fluorination Process | GE HEALTHCARE AS (NO) | 2015-11-19 | — | — | US | disclosed |
| US-9126961-B2 | Fluorination process | GE HEALTHCARE LIMITED (GB) | 2015-09-08 | — | — | US | disclosed |
| US-9126961-B2 | Fluorination process | GE HEALTHCARE LIMITED (GB) | 2015-09-08 | — | — | US | disclosed |
| US-20130225829-A1 | FLUORINATION PROCESS | GE HEALTHCARE AS (NO) | 2013-08-29 | — | — | US | disclosed |
| US-20130225829-A1 | FLUORINATION PROCESS | GE HEALTHCARE AS (NO) | 2013-08-29 | — | — | US | disclosed |
| US-8410312-B2 | Fluorination process of anilide derivatives and benzothiazole fluorinate derivatives as in vivo imaging agents | GE HEALTHCARE LIMITED (GB) | 2013-04-02 | — | — | US | disclosed |
| US-8410312-B2 | Fluorination process of anilide derivatives and benzothiazole fluorinate derivatives as in vivo imaging agents | GE HEALTHCARE LIMITED (GB) | 2013-04-02 | — | — | US | disclosed |
| US-20100234611-A1 | Fluorination Process of Anilide Derivatives and Benzothiazole Fluorinate Derivatives as in VIVO Imaging Agents | GE HEALTHCARE LIMITED (GB) | 2010-09-16 | — | — | US | disclosed |
| US-20100234611-A1 | Fluorination Process of Anilide Derivatives and Benzothiazole Fluorinate Derivatives as in VIVO Imaging Agents | GE HEALTHCARE LIMITED (GB) | 2010-09-16 | — | — | US | disclosed |
| US-20100056515-A1 | BENZIMIDAZOLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-03-04 | — | — | US | disclosed |
| WO-2007020400-A1 | FLUORINATION PROCESS OF ANILIDE DERIVATIVES AND BENZOTHIAZOLE FLUORINATE DERIVATIVES AS IN VIVO IMAGING AGENTS | GE HEALTHCARE LIMITED (GB) | 2007-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056515-A1 | BENZIMIDAZOLE COMPOUNDS | HRH4, SSTR5, CNR1 | MAPK1 1760/4885TSHR 168/4885ALDH1A1 1562/4885 |
| US-20150328344-A1 | Fluorination Process | CYP2F1, C1R, C1S | MAPK1 3080/4885TSHR 95/4885ALDH1A1 1369/4885 |
| US-20100234611-A1 | Fluorination Process of Anilide Derivatives and Benzothiazole Fluorinate Derivatives as in VIVO Imaging Agents | Q6ZSR9, AFF1, F9 | MAPK1 2569/4885TSHR 151/4885ALDH1A1 382/4885 |
| US-20130225829-A1 | FLUORINATION PROCESS | CYP2F1, C1R, C1S | MAPK1 3080/4885TSHR 95/4885ALDH1A1 1369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.